中国儿童保健杂志 ›› 2022, Vol. 30 ›› Issue (9): 985-988.DOI: 10.11852/zgetbjzz2022-0660

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孕期宫内血糖暴露对子代器官功能发育的影响

许钦雯1, 徐旭娟2, 俞洁3, 茅欣欣3   

  1. 1.南通大学医学院,江苏 南通 226000;
    2.南通大学附属医院;
    3.南通市妇幼保健院
  • 收稿日期:2022-05-26 修回日期:2022-06-28 发布日期:2022-09-07
  • 通讯作者: 徐旭娟,E-mail:2205434494@qq.com
  • 作者简介:许钦雯(1996-),女,江苏人,硕士研究生在读,主要研究方向为新生儿护理。
  • 基金资助:
    江苏省研究生科研与实践创新计划项目(KYCX21_3123)

Research progress on effects of intrauterine glucose exposure during pregnancy on offspring organ function development

XU Qin-wen*, XU Xu-juan, YU Jie, MAO Xin-xin   

  1. *Medical School of Nantong University, Nantong,Jiangsu 226000, China
  • Received:2022-05-26 Revised:2022-06-28 Published:2022-09-07
  • Contact: XU Xu-juan, E-mail:2205434494@qq.com

摘要: 随着孕前糖尿病及妊娠期糖尿病的发生率增高,越来越多的子代在母体孕期暴露于宫内高血糖,造成不良妊娠期结局,并且可能会对子代器官功能及远期器官发育造成负面影响。但是目前针对此类研究还相对较少,该文从眼、耳、牙齿和生殖器官等具体器官功能发育方面总结孕期宫内血糖暴露对子代的不良影响,为临床工作提供参考,并对此类器官发育予以重视并制定提前干预措施。

关键词: 血糖暴露, 妊娠期糖尿病, 子代, 器官发育

Abstract: With the increase in the incidence of pregestational diabetes and gestational diabetes, more and more offspring are exposed to intrauterine hyperglycemia, resulting in adverse pregnancy outcomes and possibly negative effects on specific organ functions and long-term organ development. However, there are still relatively few studies on this topic.This article summarizes the adverse effects of intrauterine blood glucose exposure on offspring from the aspects of eye,ear,teeth and genitalia function development,and the development of such organs should be paid attention to and advance intervention measures should be formulated.

Key words: blood glucose exposure, gestational diabetes, offspring, organ development

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