关键词: 婴儿, 贫血, 铁缺乏, 妊娠中期, 血清铁蛋白

Abstract: Objective To investigate the effect of maternal iron levels in second trimester of pregnancy on iron-deficiency anemia (IDA) among infants aged 3~5 months. Method 127 couples of mother-baby were followed up from the second trimester of the mothers' pregnancy till the babies were 3~5 months old.Venous blood samples were collected from 127 pregnant women in the second trimesters from their umbilical cord and used for the determination of hemoglobin(Hb) and serum ferritin(SF).The infants blood samples were collected by fingerprick to measure Hb at the end of the follow-up visit.The maternal iron status and the values of SF were compared with infants IDA. Results 1) The prevalence of IDA of infants aged 3~5 months in the group of iron deficiency was 12.9% and normol iron level was 1.5% (χ²=4.62,P<0.05).2) The prevalence of umbilical cord SF<75 μg/L in the group of maternal iron deficiency was 25.8% and normol iron level was 4.6%(χ²=9.6,P<0.05).3)The prevalence of IDA of infants aged 3~5 months in the group of umbilical cord SF<75 μg/L was 31.6%,in SF≥75 μg/L was 2.8% (χ²=16.21,P<0.01). Conclusions The mild iron deficiency in the pregnant women during the second trimester could decrease the iron storage of fetus and then cause the IDA among infants aged 3~5 months.

Key words: infant, anemia, iron-deficiency, second trimester of pregancy, serum ferritin