Study on correlation between adverse outcome hypertension disorder complicating pregnancy and umbilical artery flow of fetus

journal1 ›› 2012, Vol. 20 ›› Issue (3): 218-220.

Study on correlation between adverse outcome hypertension disorder complicating pregnancy and umbilical artery flow of fetus

WANG Zhi-ming¹,ZHUANG Ru-jin²,HAN Cong-hui³,YUAN Hong-wei⁴,CHEN Su-fen¹,QIAO Su-zhen¹,XIE Ya-chun¹,FU Zhi-wei¹,GUO Lin¹,ZONG Yu-xi²,ZHANG Hui-ying¹

1 Department of Child and Adolescent Health and Maternal Health Care,Public Health College,Harbin Medical University,Harbin,Heilongjiang 150081,China;
2 Department of Obstetrics and Gynecology,the Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang 150086,China;
3 Harbin Red Cross Hospital,Harbin,Heilongjiang 150010,China;
4 Maternal and Child Care Service Centre of Mudanjiang,Mudanjiang Heilongjiang,157000,China

Received:2011-10-21 Online:2012-03-06 Published:2012-03-06

妊娠期高血压疾病患者围产儿不良结局与脐动脉血流的关系探讨

王志明¹,庄如锦²,韩聪慧³,袁宏伟⁴,陈素芬¹,乔素贞¹,解雅春¹,付智伟¹,郭琳¹,宗禹希²,张慧颖¹

1 哈尔滨医科大学公共卫生学院儿少卫生与妇幼保健教研室,黑龙江哈尔滨 150081;
2 哈尔滨医科大学附属第二医院妇产科,黑龙江哈尔滨 150086;
3 哈尔滨市红十字中心医院,黑龙江哈尔滨 150010;
4 牡丹江市妇幼保健院,黑龙江牡丹江 157000

通讯作者: 张慧颖,E-mail: zhysxj@yahoo.com.cn
作者简介:王志明(1985-)男,河北人,在读硕士,主要研究方向为妇幼保健
基金资助:
国家自然科学基金(30771818,81172682)

Abstract

Abstract: 【Objective】 To study the impact of hypertension disorder complicating pregnancy(HDCP) on pregnancy outcome and to investigate the relationship between index of umbilical artery blood flow and pregnancy adverse outcomes. 【Method】 A prospective survey of 57 HDCP patients and 59 normal pregnant women were selected,the perinatal outcomes were observed,and the index of fetal growth and umbilical artery blood flow were recorded. 【Results】 In the incidence rates of neonate asphyxia,premature labor,fetal low birth weight,and the index of umbilical artery blood flow,HDCP group were significantly higher than those of normal group(P<0.05).Between umbilical artery blood flow and pregnancy outcomes,there was a significant negative correlation. 【Conclusions】 Adverse pregnancy outcomes and abnormal umbilical artery blood flow indices are more likely to appear in HDCP mothers. Indices of uterine artery flow can predict the occur of adverse pregnancy outcomes.

Key words: hypertension disorder complicating pregnancy, perinatal outcome, umbilical artery blood flow

摘要： 【目的】研究妊娠期高血压疾病(hypertension disorder complicating pregnancy,HDCP)对围产儿结局的影响及胎儿脐动脉血流变化与围产儿不良结局的关系。【方法】对57例妊娠期高血压疾病孕产妇和59例正常妊娠孕产妇的妊娠结局进行观察,测量胎儿脐动脉血流指标并观察两组围产儿结局。【结果】 HDCP组围产儿的不良结局在新生儿窒息、早产和低出生体重方面的发生率均高于正常组(P<0.05);两组在脐动脉血流搏动指数(PI)、阻力指数(RI)、收缩压最大血流速度与舒张末期最大血流速度比值(S/D)等三个指标上存在的差异有统计学意义(P<0.05)。胎儿脐动脉血流指标与围产儿出生结局呈负相关关系。【结论】 HDCP患者更容易发生围产儿不良结局,胎儿脐动脉血流指标更易出现异常。脐动脉血流指标RI和S/D比值可以用来预测围产儿不良结局的发生。

关键词: 妊娠期高血压, 围产儿结局, 脐动脉血流

CLC Number:

R722.1

WANG Zhi-ming,ZHUANG Ru-jin,HAN Cong-hui,YUAN Hong-wei,CHEN Su-fen,QIAO Su-zhen,XIE Ya-chun,FU Zhi-wei,GUO Lin,ZONG Yu-xi,ZHANG Hui-ying. Study on correlation between adverse outcome hypertension disorder complicating pregnancy and umbilical artery flow of fetus[J]. journal1, 2012, 20(3): 218-220.

王志明,庄如锦,韩聪慧,袁宏伟,陈素芬,乔素贞,解雅春,付智伟,郭琳,宗禹希,张慧颖. 妊娠期高血压疾病患者围产儿不良结局与脐动脉血流的关系探讨[J]. 中国儿童保健杂志, 2012, 20(3): 218-220.

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