中国儿童保健杂志 ›› 2019, Vol. 27 ›› Issue (11): 1215-1218.DOI: 10.11852/zgetbjzz2018-1314

• 临床研究与分析 • 上一篇    下一篇

儿童血清维生素A在不同年龄阶段横断面研究

张旭光1, 陈彦平1, 陈冬凯1, 张冬梅1, 刘丽1, 井鸿1, 侯绍英2   

  1. 1 哈尔滨市儿童医院儿童保健科,黑龙江 哈尔滨 150010;
    2 哈尔滨医科大学公共卫生学院营养与食品卫生学教研室,黑龙江 哈尔滨 150081
  • 收稿日期:2019-01-09 发布日期:2019-11-10 出版日期:2019-11-10
  • 通讯作者: 侯绍英,E-mail:hsy3982@163.com
  • 作者简介:张旭光(1984-),男,黑龙江人,主治医师,博士学位,主要研究方向为营养与疾病相关性的研究。
  • 基金资助:
    黑龙江省卫生计生委科研课题(2017-234)

Cross-sectional study on serum vitamin A level in children aged 0 to 16 years in different ages

ZHANG Xu-guang1, CHEN Yan-ping1, CHEN Dong-kai1, ZHANG Dong-mei1, LIU Li1, JING Hong1, HOU Shao-ying2   

  1. 1 Department of Child Health Care,Harbin Children′s Hospital,Harbin,Heilongjiang 150010,China;
    2 Department of Nutrition and Food Hygiene,Harbin Medical University,Harbin,Heilongjiang 150081,China
  • Received:2019-01-09 Online:2019-11-10 Published:2019-11-10
  • Contact: HOU Shao-ying,E-mail:hsy3982@163.com

摘要: 目的 了解儿童血清维生素A(VA)的营养现状,为儿童科学补充VA提供更多依据。方法 采用横断面研究,选择于2017年9月—2018 年8月在哈尔滨市儿童医院儿童保健门诊进行常规体检的3 163名0~16岁健康儿童为研究对象。收集儿童的年龄及性别等基本信息,采用高效液相色谱法检测儿童的血清VA水平。结果 3 163名0~16岁儿童血清VA平均水平为(0.30±0.08)mg/L;0~、0.5~、1~、3~、6~、12~16岁的儿童血清VA水平分别为(0.20±0.04)、(0.23±0.04)、(0.33±0.06)、(0.30±0.05)、(0.35±0.06)mg/L以及(0.44±0.08)mg/L;6月龄以上儿童整体血清VA异常率为52.2%(1 572/3 012),其中VA缺乏率和不足率分别为5.7%(172/3 012)和46.5%(1 400/3 012);0.5~组血清VA异常率最高,高达98.8 %,不同年龄组儿童血清VA异常率差异均有统计学意义(χ2=998.70,P<0.001)。结论 儿童的VA营养不良仍然是一项严峻的公共卫生问题,应更多的关注VA不足/缺乏率较高的儿童群体。

关键词: 维生素A水平, 儿童, 横断面研究

Abstract: Objective To investigate vitamin A level of children,in order to provide theoretical basis for scientific supplement of vitamin A. Methods A cross-sectional study was conducted. Totally 3 163 individuals aged 0 to 16 years who took physical examination in Child Care Clinic of Harbin Children′s Hospital from September,2017 to August,2018 were enrolled in this study. Information of participants such as gender and age were recorded. Serum level of vitamin A was determined by high performance liquid chromatography. Results The average level of serum vitamin A was(0.30±0.08) mg/L for all participants,and were(0.20±0.04),(0.23±0.04),(0.33±0.06),(0.30±0.05),(0.35±0.06)mg/L and(0.44±0.08) mg/L for 0—,0.5—,1—,3—,6— and 6—12 years old groups,respectively. The overall incidences of vitamin A abnormal in children aged over 6 months were 52.2%(1 572/3 012),in which the incidence of vitamin A deficiency and insufficiency were 5.7 %(172/3 012) and 46.5%(1 400/3 012),respectively. The prevalence of abnormal level of vitamin A was 98.8 % in children more than 6 months old. There was significant difference on the rate of abnormal level of vitamin A among children in different age groups(χ2=998.70,P<0.001). Conclusion Vitamin A malnutrition is still a serious public health problem and more attention is supposed to be paid to children with high rate of vitamin A deficiency and insufficiency.

Key words: vitaminAlevel, children, cross-sectionalstudy

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