关键词: 维生素A水平, 儿童, 横断面研究

Abstract: Objective To investigate vitamin A level of children,in order to provide theoretical basis for scientific supplement of vitamin A. Methods A cross-sectional study was conducted. Totally 3 163 individuals aged 0 to 16 years who took physical examination in Child Care Clinic of Harbin Children′s Hospital from September,2017 to August,2018 were enrolled in this study. Information of participants such as gender and age were recorded. Serum level of vitamin A was determined by high performance liquid chromatography. Results The average level of serum vitamin A was(0.30±0.08) mg/L for all participants,and were(0.20±0.04),(0.23±0.04),(0.33±0.06),(0.30±0.05),(0.35±0.06)mg/L and(0.44±0.08) mg/L for 0—,0.5—,1—,3—,6— and 6—12 years old groups,respectively. The overall incidences of vitamin A abnormal in children aged over 6 months were 52.2%(1 572/3 012),in which the incidence of vitamin A deficiency and insufficiency were 5.7 %(172/3 012) and 46.5%(1 400/3 012),respectively. The prevalence of abnormal level of vitamin A was 98.8 % in children more than 6 months old. There was significant difference on the rate of abnormal level of vitamin A among children in different age groups(χ²=998.70,P＜0.001). Conclusion Vitamin A malnutrition is still a serious public health problem and more attention is supposed to be paid to children with high rate of vitamin A deficiency and insufficiency.

Key words: vitaminAlevel, children, cross-sectionalstudy