关键词: 新生儿黄疸, 茵栀黄口服液, 中药水疗, 沐浴

Abstract:

AIM: To observe the therapeutic effect of medicated bath hydrotherapy combined with Yinzhihuang oral liquid on neonatal jaundice. METHODS: A total of 392 neonates with jaundice were selected from March 2016 to January 2018 in our hospital, which were randomly divided into hydrotherapy group and shower group, each with 196 cases. Both groups took Yinzhihuang oral liquid. The hydrotherapy group was supplemented with medicated bath hydrotherapy, and the shower group was given routine shower. The following indexes, including jaundice index, jaundice regression time, weight change, TBIL, ALT, TBA, CRP, IL-6, IL-8, IgA, IgG and IgM levels, and changes in red cell immune function were compared between these two groups. RESULTS:After treatment, the jaundice index of the medicated bath hydrotherapy group was lower than that of the shower group, and the regression time of the jaundice was significantly shorter, while the weight of the children after treatment was higher than that of the shower group with significant differences (P<0.05). After treatment, serum levels of TBIL, ALT, and TBA in the medicated bath hydrotherapy group were lower than those in the shower group, and the difference was statistically significant (P<0.05). The levels of serum CRP, IL-6, and IL-8 in the Chinese medicine hydrotherapy group were lower than those in the shower group, and the difference was significant (P<0.05). The plasma levels of IgA, IgG, IgM, and RBC-C3bR in the medicated bath hydrotherapy group were significantly higher than those in the shower group. The difference was statistically significant (P<0.05). CONCLUSION: The treatment of Yinzhihuang oral liquid supplemented with medicated bath hydrotherapy can effectively improve the neonatal jaundice and contribute to the improvement of children's immunity.

Key words: neonatal jaundice, Yinzhihuang oral liquid, medicated bath hydrotherapy, shower