红芪及其活性成分抗肿瘤作用的研究进展

doi:10.12092/j.issn.1009-2501.2025.08.013

摘要/Abstract

摘要： 红芪是甘肃省特色道地药材,以“米仓红芪”为佳。现代药学研究表明其有多糖类及黄酮类等药效成分,具有良好的抗肿瘤效果,能够抑制肺癌、肝癌及乳腺癌等多种癌症的发生与发展。癌症被列为全球第二大致死病因,且发病率和死亡率逐年上升,严重影响生活质量。目前,随着中医药现代化的发展,中药在治疗恶性肿瘤方面已有重大突破。基于此,通过整理近年来国内外相关文献资料,对红芪及其活性成分抗肿瘤作用及机制进行总结归纳,为阐明红芪抗肿瘤作用物质基础的研究提供科学依据,促进红芪产业发展。

关键词: 红芪, 活性成分, 抗肿瘤, 作用机制

Abstract: Hedysari radix is the characteristic chinese medicine of Gansu Province, with "MiCang Hedysari radix" as the best. Modern pharmacological research has shown that it has polysaccharides and flavonoids, which have good anti-tumor effects and can inhibit the occurrence and development of various cancers, such as lung cancer, liver cancer, and breast cancer. Cancer is ranked as the second leading cause of death in the world, and the morbidity and mortality rates are increasing year by year, seriously affecting the quality of life. At present, with the modernization of Traditional Chinese Medicine (TCM), there has been a significant breakthrough in the treatment of malignant tumors with TCM. Based on this, by collating the relevant literature at home and abroad in recent years, the anti-tumor effects and mechanisms of Hedysari radix and its active ingredients are summarized to provide a scientific basis for the study of elucidating the material basis of the anti-tumor effects of Hedysari radix and to promote the development of the Hedysari radix industry.

Key words: Hedysari radix, active ingredients, anti-tumor, mechanism of action

中图分类号:

R73
R932

魏小成, 李昕蓉, 何军刚, 李旭, 强正泽, 王燕, 王明伟, 李成义. 红芪及其活性成分抗肿瘤作用的研究进展[J]. 中国临床药理学与治疗学, 2025, 30(8): 1112-1121.

WEI Xiaocheng, LI Xinrong, HE Jungang, LI Xu, QIANG Zhengze, WANG Yan, WANG Mingwei, LI Chengyi. Research progress on antitumor effects of Hedysari radix and active components[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2025, 30(8): 1112-1121.

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