1 La Quaglia MP. Osteosarcoma: specific tumour managementand results. Chest Surg Clin North Am, 1998:8:77 2 Bicci G, Picci P, PignaUi G. Neoadjuvant chemotherapyfor nonmelastalic osteosarcoma of the extremities. Clin Orthop, 199I;279:87 3 Kamen BA, Winich NJ. High dose methotrexate therapy: insecure rationale. Biochem Pharmacol, 1998;37:2713 4 Treon SP, Chabner BA,. Concepts in use of high-dose methotrexate therapy. Clin Chem, 1996;42: 1322 5 Sater G, Alvegarcl TA, Elomaa I, et al. Che-motherapy for osteosarcomd ancl Ewing's asreoma. Acta Orthop Scand, 1997;68s: 120 6 Hortobagyi GN. Anthracyclines in the treatment of cancer. Drugs, 1997;54s: 1 7 Jaffe N, Raymond Ak, Ayala A. Effect of cumula-live courses of intra-arterial cis-diamine-dichloro platimum D on the primary tumour in osteosarco-ma. Cancer, 1989;63:63 8 Van Oosterom AT, Verweij J. New drugs for the treatment of sarcoma. Hematol Oncol Clin North Am, 1995;9:909 9 Souhami Rl,'Craft AW, Eijken VD, et aL. Ran-domised trial of two regimens of chemotherapy in operable osteosarcoma. Lancet, 1997;350:911 10 Bruland OS, Pihl A. On current management of osteosarcoma. A critical evaluation and a proposal for modified treatment strategy. Eur J Cancer, 1997;33:1725 11 Baldini N, Scotlandi K, Barbanti-Brodano G, etui. Expression of P-glycoprotein in high-grade os-teosarcoma in relation to clinical outcome. New Eng J Med, 1995:333:1380 12 Chan HSL, Grogan TM, Haddad G, et al. P-glycoprotein expression: Clinical determinant in ihe response to osteosarcoma chemotherapy. J Natl Cancer Inst, 1997;89:1706 13 Kleinerman Es. Biologic therapy for osteosarcoma using liposome-encapsulated muramyl tripeptide. Hematol Oncol Clin North Am, 1995;9:227 14 Kleinerman ESJano JB, Johnston DA. Efficacy of liposomal muramyl tripeptidc in the treatment of relapsed osteosarcoma. An J Clin Oncol, 1995; 18:93 15 Worht LL, Jaffe N, Benjaming RS, et al. Phase II study of recombinant interleukin-1 aplha and etoposide in patients with relapsed osteosarco-ma. Clin Cancer Res, 1997;3:1721 16 Panzer A. Melatonin in osteosarcoma, an effective drug. Med Hypothes, 1997;48:523 17 Chwon J, Ko Sc, Gardner TA, et al. Chemogene therapy-osteocalicin promoter-based suicide gene therapy in combination with methotrexate in a murine osteosarcoma model. Cancer Gene Thera-py, 1997;4:359 18 Khanna C, Anderson PM, Katsanis E, et al. Interleukin-2 liposo.e inhalation therapy is safe and effective for dog with spontaneous pulmonary metastasises,. Cancer, 1997:79:1409 19 Hayakawa M, Kawaguchi S, Ishi S, et al. B 7-1-transfected tumour vaccine counteracts chemotherapy-induccd immunosuppression and prolongs the survival of rats bearing highly metastatic osteosarcome cells. Int J Cancer, 199; 71:109 20 Jaffe N, Patel SR, Benjamin RS. Chemotherapy in osteosarcoma. Hematol Oncol Clin North Am, 1995;9:825 |