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中国临床药理学与治疗学 ›› 2002, Vol. 7 ›› Issue (3): 252-254.

• 临床研究 • 上一篇    下一篇

吗丁啉治疗胃食管反流相关性支气管哮喘疗效观察

李运泉, 孔海鸿, 李民华   

  1. 广东省顺德市乐从医院, 顺德 528315
  • 收稿日期:2002-01-30 修回日期:2002-03-25 发布日期:2020-12-01

Effect of motilium on 50 cases of bronchial asthma associated with gastroe-sophageal reflux

LI Yun-Quan, KONG Hai-Hong, LI Min-Hua   

  1. Lecong Hospital of Shunde City, Shunde 528315
  • Received:2002-01-30 Revised:2002-03-25 Published:2020-12-01

摘要: 目的: 观察吗丁啉对胃、食管反流相关性支气管哮喘的疗效。方法: 对50 例胃、食管反流相关性支气管哮喘患者, 在支气管哮喘急性发作时给予常规对症治疗的同时, 给予口服吗丁啉 20 mg, tid;伴有慢性胃炎者加服雷米替丁 0.3 g 、阿莫西林0.5 g 及灭滴灵 0.2 g, tid;有胃酸过多者夜间加服洛赛克(losec) 20 mg 。4 wk 为一个疗程, 第一个疗程结束后, 停药观察1 ~ 4 wk, 病情复发者继服第二个疗程。结果: 第一个疗程结束后, 有45 例病人停止发病, 观察6 mon 病情未复发。5 例在停药1 ~ 4 wk 病情复发者, 继服第二个疗程后, 有4 例停止发病, 随访6 mon 未复发, 1 例发病次数减少一半。结论: 吗丁啉用以预防和治疗胃、食管反流相关性支气管哮喘具有良好效果。

关键词: 吗丁啉, 胃、食管反流, 相关性哮喘

Abstract: AIM: To observe the effect of motilium on bronchial asthma associated with gastroesophageal reflux (GER-BA).METHODS: 50 cases of GER-BA, were treated with routine anti-asthma and motilium 20 mg tid, ranitidine 0.3 g, amoxicillin 0.5 g and metronidazolum 0.2 g tid for chronic gastritis cases, and losec 20 mg for the gastric acid rdflux at night.The treatment lasted for 1-4 wk, and then stopped to observe the response of the treat-meat.The recurrent cases would be treated as the above again.RESULTS: 45 cases were curedin the 4 wk, no case recrudescedin 6 mon.5 cases neededanother the treatment for 1-4 wk since the recurrence, and 4 of the 5 cases were cured.CONCLUSION: Motilium has a good curative effect in preventing and curing bronchial asthma associated with gastroesophageal reflux.

Key words: mtilium, gastroesophageal reflux, bronchial asthma

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