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中国临床药理学与治疗学 ›› 2002, Vol. 7 ›› Issue (5): 428-430.

• 研究原著 • 上一篇    下一篇

衍阳口服液对去势大鼠性功能的影响

范娟, 许士凯1, 陈光亮2   

  1. 江苏省连云港市第二人民医院药剂科, 连云港 222001;
    1上海仕凯生命科学研究所性药学研究室, 上海 200422;
    2安徽中医学院天然药物研究所, 合肥 230038
  • 收稿日期:2002-05-16 修回日期:2002-06-20 发布日期:2020-11-26
  • 通讯作者: 范娟, 女, 主管药师, 主要从事药理学及药剂学工作。Tel:0518-5433484 Email:fj22@sina.com.cn
  • 作者简介:许士凯, 男, 教授, 国家自然科学基金委员会生命科学部委员, 本刊编委, 主要从事抗衰老药理学与性药学的研究。Tel:021-66345359 E-mail:XSK0809 @shtdu.edu.cn

Effect of yanyang oral liquid on sexual function in a rat model of castration

FAN Juan, XU Shi-Kai1, CHEN Guan-Lian2   

  1. Department of Pharmaceutics, Second Hospital of Lianyuanggan City, Lianyuanggan 222001;
    1Department of Sexual Pharmacy, Shanghai Shikai Institute of Life Science, Shanghai, 200422;
    2Anhui Traditional Chinese Medical College,Hefei 230038
  • Received:2002-05-16 Revised:2002-06-20 Published:2020-11-26

摘要: 目的 观察衍阳口服液对去势大鼠性功能的影响。 方法 建立Wistar 大鼠去势模型, 给予去势大鼠按剂量4.9 g·kg-1、9.6 g·kg-12 个剂量组连续灌服衍阳口服液21 d, 采用性功能测定法进行对比观察动物性行为的变化。 结果 与去势模型组比较, 衍阳口服液能使去势大鼠下降的交配次数明显增加(P <0.01);可减少去势大鼠前列腺与提肛肌的重量下降P <0.01)。上述作用与男宝组相似。 结论 衍阳口服液具有补肾壮阳作用。

关键词: 衍阳口服液, 去势, 性功能, 壮阳

Abstract: AIM: To observe the effect of yangyang oral liquid on sexual function in a rat model of castration. METHODS: Rat castration models were given each yangyang oral liquid (4.9 and 9.6 g·kg-1) (ig) for 21 days.The sexual test was adopted to investigate sexual behavior in the rat models. RESULTS: Like nanbao capsule, yangyang oral liquid could significantly enhance the frequency of copulation in the rat models (P < 0.01), and in yangyang oral liquid group, the weight of prostate gland and lavator was lost became thinner, as compared with those in the control group (P < 0.01). CONCULUTION: Yangyang oral liquid can increase the sexual function in rat castration models.

Key words: yangyang oral liquid, castration, sexual function, invigorating Yang

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