欢迎访问《中国临床药理学与治疗学》杂志官方网站,今天是

中国临床药理学与治疗学 ›› 2004, Vol. 9 ›› Issue (11): 1201-1204.

• 综述 •    下一篇

血管紧张素受体阻滞剂治疗慢性进展性肾病的研究进展

吴冀宁 综述, 刘必成 审校   

  1. 东南大学肾脏病研究所,东南大学附属中大医院肾科,南京 2100009,江苏
  • 收稿日期:2004-08-09 修回日期:2004-10-02 出版日期:2004-11-26 发布日期:2020-11-19
  • 通讯作者: 刘必成,男,教授,硕士生导师,研究方向:慢性肾脏纤维化的机制,Tel: 025-83272137 E-mail:njwulq@jlonline.com
  • 作者简介:吴冀宁, 女, 硕士研究生。

Current researches of angiotensin receptor blockers in treatment of patients with chronic progressive renal disease

WU Ji-Ning, LIU Bi-Cheng   

  1. Department of Nephrology,Zhongda Hospital,Southeast Unitersity, Nanjing 210000, Jiangsu, China
  • Received:2004-08-09 Revised:2004-10-02 Online:2004-11-26 Published:2020-11-19

摘要: 肾素-血管紧张素系统(RA)S 在慢性肾病的进展中起着非常重要的作用。阻断RAS作用已成为慢性进展性肾病(CPRD)治疗的主要手段之一。血管紧张素受体阻滞剂(ARB) 以其副反应小、安全性高等特点受到广泛关注。近十年的研究表明ARB可以从多方面确实有效地延缓慢性肾病的进展,并为CPRD的临床治疗提供了循证医学证据。

关键词: 慢性进展性肾病, 血管紧张素受体阻滞剂, 血管紧张素, 高血压, 蛋白尿, 肾脏纤维化

Abstract: The renin-angiotensin system plays an important role in the progression of chronic renal disases. At present, the main lapproach for treating the chronie prognessive renal disease is to block the role of renin-an-giotensin system. Recently,angiotensin receptor blockers have being realized in width with its few side fect and good safety. A number of experimental and clinical resuls in recent 10 years have indicated that ARB can prevent or even reverse the progression of chronic renal diseases in many ways effectively and provided great evidences for current therapy of CPRD.

Key words: chronic progressive renal disease, angiolenin rcepor blocker, teatment, bypertension, protenuria, renal fibrosis

中图分类号: