欢迎访问《中国临床药理学与治疗学》杂志官方网站,今天是

中国临床药理学与治疗学 ›› 2005, Vol. 10 ›› Issue (8): 929-931.

• 研究原著 • 上一篇    下一篇

扶正除疫颗粒对免疫功能低下动物免疫调节的影响

宫晓燕, 曲晓波1, 王泽玉   

  1. 长春中医学院附属医院呼吸内科, 1临床医学部, 长春 130021, 吉林
  • 收稿日期:2005-07-25 修回日期:2005-08-16 发布日期:2020-11-22
  • 作者简介:宫晓燕,女,医学硕士,教授,研究方向:呼吸病科研与临床工作。Tel:0536-2313934 E-mail:zeyu781022@163.com
  • 基金资助:
    吉林省科学技术厅传染性非典型肺炎专向课题(No20030901)

Influence on immunological regulation of fuzhenchuyi granule in mice with immune hypofunction

GONG Xiao-yan, QU Xiao-bo1, WANG Ze-yu   

  1. Affiliated Hospital, 1Department of Chlinical Medicine, Changchun College of Traditional Chinese Medicine, Changchun 130021, Jilin, China
  • Received:2005-07-25 Revised:2005-08-16 Published:2020-11-22

摘要: 目的: 观察扶正除疫颗粒对免疫功能低下实验动物免疫调节的影响。方法: 以腹腔注射环磷酰胺(CTX)建立免疫功能低下小鼠模型。采用分光光度法、细胞计数法分别观察其单核吞噬细胞吞噬功能、血清溶血素、溶血空斑形成及淋巴细胞转化率。结果: 扶正除疫颗粒可显著提高免疫功能低下小鼠网状内皮系统(RES)吞噬细胞的功能,促进溶血素水平升高及溶血空斑形成,提高淋巴细胞转化率。结论: 扶正除疫颗粒对免疫功能低下动物非特异性免疫、体液免疫及细胞免疫功能有正性调节作用。

关键词: 扶正除疫颗粒, 免疫调节, 非特异性免疫, 体液免疫, 细胞免疫

Abstract: AIM: To observe the immunological regulation of the fuzhenchuyi granule in mice with immune hypofunction.METHODS: The immune hypofunction mouse models were made by intraperitoneal injecting cyclophosphamide in mice.The mononuclear phagocyte englobement function, serum erythrocytolysin, haematolysis plaque formation and lymphocyte conversion ratio were determined by the absorption spectrometry and cytometry.RESULTS: The fuzhenchuyi granule enhanced immuned hypofunctional mouse reticulo-endothelium system and cytophagous function encouraged the level of erythrocytolysin and haematolysis plaque formation, and boosted lymphocyte transformation rate.CONCLUSION: The fuzhenchuyi granule shows a positive regulation, including nonspecific immunity, humoral immunity and cellular immune function, in mice with immune hypofunctional.

Key words: the fuzhenchuyi granule, immunity adjust, nonspecific immunity, iumoral immunity, cellular immune function

中图分类号: