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中国临床药理学与治疗学 ›› 2006, Vol. 11 ›› Issue (2): 141-144.

• 综述 • 上一篇    下一篇

阿托伐他汀非调脂作用的最新进展

孙 姗, 吴尚勤   

  1. 天津市胸科医院心内七科, 天津 300051
  • 收稿日期:2005-12-05 修回日期:2006-01-10 出版日期:2006-02-06 发布日期:2020-10-26

Most advanced review on non-lipid-regulating action of atorvastatin

SUN shan, WU Shang-qin   

  1. Seventh Department of Cardiology , Tianjin Chest Hospital, Tianjin 300051 , China
  • Received:2005-12-05 Revised:2006-01-10 Online:2006-02-06 Published:2020-10-26

摘要: 近来研究表明, 他汀类药物能有效改善冠心 病患者的预后, 该效应除与他汀类调脂作用有关外, 还和其非调脂作用密切相关。阿托伐他汀是目前国 内最新一代他汀类药物。本文综合国内外最新报 道, 全面阐述了阿托伐他汀非调脂效应在冠心病防 治中的作用地位及安全性 。

关键词: 阿托伐他汀 , 非调脂作用 , 冠心病, 炎症, 安 全性

Abstract: Recent reports have indicated that Statins could remarkably improve the prognosis of patients suf- fered from coronary artery disease .And this effect is not only due to Statin' s lipid-regulating function, but also correlated to its non-lipid-regulating action .Atorvastatin is the latest kind of statins .In this article, we specified the non-lipid-regulating effect of Atorvastatin in the preven- tion and therapy to coronary artery disease .Furthermore, we summarized its corresponding clinical evaluation or se- curity .

Key words: Atorvastatin , non-lipid-regulating ef- fect , coronary artery disease , inflammation , security

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