早产儿视网膜病与氧疗的关系

摘要/Abstract

摘要： 目前早产儿视网膜病(ROP) 已引起社会的普遍关注, 相关报道认为早产低出生体重是发病的根本基础, 对于某些小孕龄、发育差的低出生体重早产儿来说, 不合理氧疗是ROP 的重要诱发因素。不合理氧疗包括吸氧浓度高、时间长以及吸氧时的氧分压大幅波动。本文重点介绍ROP 与氧疗的关系, 以探讨其确切发病原因和机制, 寻找有效的预防措施。

关键词: 早产儿, 早产, 视网膜疾病, 氧疗

Abstract: Retinopathy of prematurity (ROP) has evoken generally social attention now, and correlated reports point that prematurity and low birth weight could be the foundation of ROP, and irrationable oxygen therapy could be the significantly causative factor for some premature infants with shorter gestational age, maldevelopment and low birth weight. The irrationable oxygen therapy includes aspiration of hyperxia, longtime aspiration of oxygen and striking fluctuation of oxygen partial pressure. The review would summarize the relationship between retinopathy of prematurity and oxygen therapy according to lately research reports, and search for the certain cause, pathogenesy and the method of prevention and cure of ROP.

Key words: premature infant, prematurity, retinal disease, oxygen therapy

中图分类号:

R722. 6

赵海廷, 茅双根. 早产儿视网膜病与氧疗的关系[J]. 中国临床药理学与治疗学, 2008, 13(5): 596-600.

ZHAO Hai-ting, MAO Shuang-gen. Relationship between retinopathy of prematurity and oxygen therapy[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(5): 596-600.

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