大蒜素雾化吸入辅助治疗慢性支气管炎急性发作患者的疗效观察

中国临床药理学与治疗学 ›› 2008, Vol. 13 ›› Issue (9): 1058-1061.

大蒜素雾化吸入辅助治疗慢性支气管炎急性发作患者的疗效观察

刘一鸣, 王小翠

安康职业技术学院, 安康725000, 陕西

收稿日期:2008-07-16 修回日期:2008-08-15 出版日期:2008-09-26 发布日期:2020-10-13
作者简介:刘一鸣, 男, 副教授, 研究方向:呼吸系统疾病的预防与治疗。Tel:0915-3285004 E-mail:lymwxc@163.com

Clinical evaluation on the efficacy of inhaling atomized garlicin injection for assistant treating acute exacerbations of chronic bronchitis

LIU Yi-ming, WANG Xiao-cui

Ankang Occupation Technical College, Ankang 725000, Shaanxi, China

Received:2008-07-16 Revised:2008-08-15 Online:2008-09-26 Published:2020-10-13

摘要/Abstract

摘要： 目的:探讨大蒜素注射液雾化吸入辅助治疗慢性支气管炎急性发作患者的效果与机制。方法:将116 例慢性支气管炎患者随机分成治疗组64 例和对照组52 例, 对照组运用西医常规治疗(抗感染, 平喘及对症处理), 治疗组在西医治疗基础上加用大蒜素注射液雾化吸入治疗。观察两组的治疗总有效率, 并检测所有病例治疗前后氧分压、二氧化碳分压、血清TNF-α和IFN-γ含量(ELISA 法检测) 。结果:治疗组总有效率为93.75%, 对照组总有效率为67.31%, 两组疗效比较差异有统计学意义(P<0.05), 治疗组优于对照组。两组的氧分压、二氧化碳分压及外周血TNF-α、IFN-γ含量比较均有统计学差异, 治疗组优于对照组。结论:大蒜素注射液雾化吸入配合西医常规治疗可以有效改善慢性支气管炎患者急性发作期症状并缩短病程。

关键词: 慢性支气管炎, 急性发作, 大蒜素注射液, 雾化吸入

Abstract: AIM: To evaluate the efficacy of inhaling atomized garlicin injection for assistant treating acute exacerbations of chronic bronchitis.METHODS: Based on the conventional treatment, 64 cases in the treatment group were given inhaled atomized garlicin injection, while other 52 cases in the control group were treated by the conventional treatment.Total effective rates of two groups were observed, the oxygen partial pressure, carbon dioxide partial pressure, the TNF-αand IFN-γ of blood serum in all cases were detected before and after treatment.RESULTS: The total effective rate of the treatment group is 93.75% and that of the control group is 67.31%, which shows a notable diference between the two groups (P<0.05). The curative effects for PO₂, PaCO₂ and concentrations of serum TNF-αand IFN-γ also show notable diference between the two groups, that is, the treatment group has got better effect.CONCLUSION: Inhaled atomized garlicin injection in treating patients with acute exacerbation of chronic bronchitis can improve symptom, shorten the course of disease.

Key words: chronicbronchitis, acuteexacerbations, garlicininjection, inhaledatomized

中图分类号:

R562.2⁺1

刘一鸣, 王小翠. 大蒜素雾化吸入辅助治疗慢性支气管炎急性发作患者的疗效观察[J]. 中国临床药理学与治疗学, 2008, 13(9): 1058-1061.

LIU Yi-ming, WANG Xiao-cui. Clinical evaluation on the efficacy of inhaling atomized garlicin injection for assistant treating acute exacerbations of chronic bronchitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2008, 13(9): 1058-1061.

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