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中国临床药理学与治疗学 ›› 2009, Vol. 14 ›› Issue (10): 1164-1167.

• 药物治疗学 • 上一篇    下一篇

特利加压素治疗肝肾综合征的疗效分析

俞哲, 叶坚虹, 王琛, 茹仁萍   

  1. 杭州市第六人民医院, 杭州 310014, 浙江
  • 收稿日期:2009-08-04 修回日期:2009-10-09 发布日期:2020-10-29
  • 作者简介:俞哲,男,硕士,研究方向:重症肝病诊治。Tel:13165968696 E-mail:ellison007@163.com

Observation of terlipressin in management of patients with hepatorenal syndrome

YU Zhe, YE Jiang-hong, WANG Che, RU Ren-ping   

  1. Sixth People Hospital of Hangzhou City, Hangzhou 310014, Zhejiang, China
  • Received:2009-08-04 Revised:2009-10-09 Published:2020-10-29

摘要: 目的 观察特利加压素治疗肝肾综合征的疗效。方法 60 例患者分为2 组, 在内科综合治疗基础上, A 组使用特利加压素, B 组为对照组,观察患者临床表现、实验室指标、转归等。结果 A 组较B 组平均动脉压增高、尿量增多、血Cr 降低, 有效率增加, 差异有统计学意义。结论 特利加压素对肝肾综合征的治疗安全、有效。

关键词: 肝肾综合征, 特利加压素, 血管活性药物, 药物治疗

Abstract: AIM: To observe the effect of terlipressin in the management of patients with hepatorenal syndrome. METHODS: 60 patients were divided into two groups.In Group A, terlipressine was used and Group B was control group.The clinical manifestation, laboratory examination, turnover were observed during treatment. RESULTS: Compared with Group B, the effective power, the mean arterial pressure and the total urine output were increased significantly, the serum creatinine level was decreased remarkably. CONCLUSION: Terlipressin is safe and effective on hepatorenal syndrome with minute adverse reaction.

Key words: hepatorenal syndrome, tterlipressin, vasoactive agent, pharmacotherapy

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