当归六黄汤合煎、分煎样品的体外抗菌、抗炎作用比较

中国临床药理学与治疗学 ›› 2009, Vol. 14 ›› Issue (8): 877-882.

当归六黄汤合煎、分煎样品的体外抗菌、抗炎作用比较

钟正灵¹, 谢海棠¹, 张丽艳², 童九翠¹, 李娟¹, 田维毅², 梁光义², 先桂花³

¹皖南医学院弋矶山医院安徽省药物临床评价中心, 芜湖 241001, 安徽;
²贵阳中医学院, 贵阳 550002, 贵州;
³芜湖华信生物药业股份有限公司, 芜湖 241006, 安徽

收稿日期:2009-06-25 修回日期:2009-07-28 出版日期:2009-08-26 发布日期:2020-10-30
通讯作者: 梁光义, 男, 教授, 博士研究生导师, 研究方向:中药化学与新药开发研究工作。
基金资助:
国家自然科学基金项目(30460154)

Comparison on in vitro antibacterial and anti-inflammation effects of the different decoctions of Dangguiliuhuang tang

ZHONG Zheng-ling¹, XIE Hai-tang¹, ZHANG Li-yan², TONG Jiu-cui¹, LI Jun¹, TIAN Wei-yi², LIANG Guang-yi², XIAN GUI-hua³

¹Anhui Provincial Center forDrug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu241001,Anhui , China;
²College of Guiyang Traditional Chinese Medical , Guiyang550002, Guizhou, China;
³Wuhui Hua-xin Pharmaceutical Co., Ltd, Wuhu 241006, Anhui, China

Received:2009-06-25 Revised:2009-07-28 Online:2009-08-26 Published:2020-10-30

摘要/Abstract

摘要： 目的: 比较当归六黄汤合煎、分煎样品体外抗菌、抗炎作用的差异。方法: 采用琼脂扩散管碟法、试管法比较抗菌作用强弱;采用小鼠耳廓肿胀法比较抗炎作用强弱。结果: 二者抗菌作用相近,分煎样品对炎症的抑制率高于合煎样品。结论: 本试验的完成为当归六黄汤中药配方颗粒的研究开发提供参考。

关键词: 当归六黄汤, 抗菌作用, 抗炎作用

Abstract: AIM: To compare the difference of in vitro antibacterial and anti-inflammatory effects of different decoctions of Dangguiliuhuang tang. METHODS: The antibacterial effects of the two kinds different decoctions were compared by the agar bridge meth-od and test tube method .The anti-inflammatory effects were compared by ear swelling test in mice. RESULTS: The antibacterial effects of the two kinds of decoctions have no significance, but the inhibition ratio of inflammation of single decoction was higher than that of combination decoction. CONCLUSION: The re-search can provide for the reference on development of Dangguiliuhuang tang .

Key words: Dangguiliuhuang tang, antibacterial effect, anti-inflammatory effect

中图分类号:

R965.2

钟正灵, 谢海棠, 张丽艳, 童九翠, 李娟, 田维毅, 梁光义, 先桂花. 当归六黄汤合煎、分煎样品的体外抗菌、抗炎作用比较[J]. 中国临床药理学与治疗学, 2009, 14(8): 877-882.

ZHONG Zheng-ling, XIE Hai-tang, ZHANG Li-yan, TONG Jiu-cui, LI Jun, TIAN Wei-yi, LIANG Guang-yi, XIAN GUI-hua. Comparison on in vitro antibacterial and anti-inflammation effects of the different decoctions of Dangguiliuhuang tang[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2009, 14(8): 877-882.

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