皂苷的抗肿瘤活性研究

摘要/Abstract

摘要： 皂苷是一类结构复杂多样的化合物,许多皂苷都具有良好的抗癌活性。本文从皂苷抗肿瘤的机理方面扼要地概括了近年来研究较多的有抗癌活性的皂苷及其抗肿瘤的构效关系,为皂苷抗肿瘤的进一步机制研究及开发新的抗癌药物提供参考。

Abstract: Saponins are structurally diverse compounds, most of which have amazing anti-tumorigenic effect. This review summarizes the role of saponins in tumor therapy, the mechanism of actions and their structure-activity relationship, thus giving some information to the futher mechanism research and new naturally occurring anti-tumor drugs discovery.

Key words: Saponin, Anti-tumor, Structure-activity relationship

中图分类号:

R969

尚丽丽, 孙建国, 谢海棠, 王广基. 皂苷的抗肿瘤活性研究[J]. 中国临床药理学与治疗学, 2010, 15(2): 225-232.

SHANG Li-li, SUN Jian-guo, XIE Hai-tang, WANG Guang-ji. Saponins in tumor therapy[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(2): 225-232.

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