舒芬太尼复合罗哌卡因应用于妊娠期糖尿病分娩镇痛的临床研究

中国临床药理学与治疗学 ›› 2010, Vol. 15 ›› Issue (8): 920-923.

舒芬太尼复合罗哌卡因应用于妊娠期糖尿病分娩镇痛的临床研究

吴玲玲, 范建辉, 尹玉竹, 王林琳, 朱娟, 侯红瑛

中山大学附属第三医院妇产科,广州 510630,广东

收稿日期:2010-07-20 修回日期:2010-08-10 出版日期:2010-08-26 发布日期:2020-09-17
通讯作者: 侯红瑛,女,副教授,硕士生导师,研究方向:产科学。E-mail: gdgzhhyy@163.com
作者简介:吴玲玲,女,硕士,主治医师,研究方向:产科学。Tel: 13711217216 E-mail: wll1990@sohu.com
基金资助:
广东省科技计划项目资助(2007B031501007)

Clinical study of sufentanil combined ropivacaine for labor pain in gestational diabetes mellitus

WU Ling-ling, FAN Jian-hui, YIN Yu-zhu, WANG Lin-lin, ZHU Juan, HOU Hong-ying

Department of Obstetrics and Gynecology, Third Affiliated Hospital of SUN Yat-sen University, Guangzhou 510630, Guangdong,China

Received:2010-07-20 Revised:2010-08-10 Online:2010-08-26 Published:2020-09-17

摘要/Abstract

摘要： 目的: 探讨舒芬太尼复合罗哌卡因应用于分娩镇痛对妊娠期糖尿病(gestational diabetes mellitus,GDM)分娩结局及产程中血糖水平的影响。方法: 125例GDM产妇,采用舒芬太尼复合罗哌卡因实施腰麻-硬膜外联合(combined spinal-epidural, CSE)分娩镇痛的60例为研究组,未选择分娩镇痛的65例为对照组,评定舒芬太尼复合罗哌卡因的镇痛效果并比较两组产妇的分娩结局及血糖水平。结果: 研究组于麻醉成功后 10 min 内均达到镇痛效果;研究组第一产程活跃期时限长于对照组 (P＜0.05),产程中剖宫产率低于对照组(P＜0.05),产程中血糖水平低于对照组 (P＜0.05)。结论: 舒芬太尼复合罗哌卡因应用于GDM的分娩镇痛效果确切,有益于产程中血糖水平的稳定,降低剖宫产率。

关键词: 舒芬太尼, 罗哌卡因, 分娩镇痛, 妊娠期糖尿病, 分娩结局, 血糖

Abstract: AIM: To evaluate the effect of sufentanil combined ropivacaine for labor anesthesia on labor outcome and blood glucose during childbirth of gestational diabetes mellitus.METHODS: 125 cases of gestational diabetes mellitus who selected vaginal delivery ,60 cases in study group received sufentanil combined ropivacaine for pain relief during childbirth, 65 cases in control group without any pain relief during childbirth, labor outcome and blood glucose during childbirth were compared between two groups.RESULTS: Patients in study group felt pain relief in ten minutes since receiving CSEA. The duration of active phase in the first stage in study group was significantly longer than that of control group (P＜0.05). Patients who received cesarean section(CS) in study group were lower than that of control group (P<0.05). Blood glucose during childbirth was significantly lower in study group than that of control group (P< 0.05).CONCLUSION: Sufentanil combined ropivacaine could alleviate labor pain,stabilize blood glucose and reduce CS rate during childbirth in GDM patients.

Key words: Sufentanil, Ropivacaine, Labor anesthesia, Gestational diabetes mellitus, Labor outcome, Blood glucose

中图分类号:

R614

吴玲玲, 范建辉, 尹玉竹, 王林琳, 朱娟, 侯红瑛. 舒芬太尼复合罗哌卡因应用于妊娠期糖尿病分娩镇痛的临床研究[J]. 中国临床药理学与治疗学, 2010, 15(8): 920-923.

WU Ling-ling, FAN Jian-hui, YIN Yu-zhu, WANG Lin-lin, ZHU Juan, HOU Hong-ying. Clinical study of sufentanil combined ropivacaine for labor pain in gestational diabetes mellitus[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2010, 15(8): 920-923.

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