比较中西医疗效评价方法在胃癌治疗应用中的差异

中国临床药理学与治疗学 ›› 2011, Vol. 16 ›› Issue (10): 1169-1173.

比较中西医疗效评价方法在胃癌治疗应用中的差异

王海波, 吴式琇, 黄庆科

浙江省温州医学院附属第一医院,温州 325000,浙江

收稿日期:2011-07-15 修回日期:2011-09-10 出版日期:2011-10-26 发布日期:2011-11-02
作者简介:王海波,男,硕士,主治中医师,研究方向:中西医结合治疗胃肠道恶性肿瘤。Tel: 13758728968, E-mail: 513841767@qq.com
基金资助:
浙江省中医药管理局资助项目(2009CA074)

Study on the methods of Chinese medicine and western medicine therapeutic evaluation for the treatment of advanced gastric cancer

WANG Hai-bo, WU Shi-xiu, HUANG Qing-ke

Department of Chinese Traditional Medicine, the First Affiliated Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang, China

Received:2011-07-15 Revised:2011-09-10 Online:2011-10-26 Published:2011-11-02

摘要/Abstract

摘要： 目的: 观察中医及西医两种疗效评价方法在进展期胃癌患者治疗中的差异。方法: 将进展期胃癌患者215例随机分为中药组115例和化疗组100例,中药组采用中药注射剂联合辩证论治汤剂治疗,化疗组采用OFL化疗方案治疗,疗程均为6周;以“中医治疗进展期胃癌患者临床受益评定标准”和“WHO实体瘤疗效评价标准”同步对胃癌患者治疗疗效进行评价。结果: 按照“WHO实体瘤疗效评价标准”进行评价,化疗组疗效较中药组升高(P<0.05),但按照“中医治疗进展期胃癌患者临床受益评定标准”评价,中药组疗效较化疗组升高(P<0.05);上述两种评价方法得出的结论存在差异。结论: 相对于“WHO实体瘤疗效评价标准”,“中医治疗进展期胃癌患者临床受益评定标准”更能反映中医药在治疗进展期胃癌治疗中的优势,值得进一步推广。

关键词: 疗效评价, 进展期胃癌, 中医药

Abstract: AIM: To investigate the difference and characteristics in Chinese medicine (CM) and Western medicine therapeutic evaluation methods in the application of advanced gastric cancer. METHODS: A total of 215 cases of advanced gastric cancer were enrolled in this study and assigned into two groups. 115 cases in the CM group were treated with CM injection combined with treatment based on syndrome differentiation. 100 cases in the chemotherapy group were treated with chemothearapy scheme. All the treatment were lasted for 6 weeks. Their short-term therapeutic effects were observed by the “clinic efficacy appraisal standard of therapy for advanced gastric cancer with CM” simultaneously and by the follow-up Western medical solid tumor's effect evaluation criterion. RESULTS: According to WHO solid tumor's effect evaluation criterion, the efficacy of the chemotherapy group was much better than that of the CM group. However, according to the “clinic efficacy appraisal standard of therapy for advanced gastric cancer with CM”, the efficacy of the CM group was better than that of the chemotherapy group. There was difference in the results of the two evaluation methods. CONCLUSION: Compared with WHO solid tumor' s effect evaluation criterion, “the clinic efficacy appraisal standard of therapy for advanced gastric cancer with CM” can reflect more features and advantages of CM for advanced gastric cancer treatment, having value for further study.

Key words: Therapeutic evaluation, Advanced gastric cancer, Chinese medicine

中图分类号:

R273

王海波, 吴式琇, 黄庆科. 比较中西医疗效评价方法在胃癌治疗应用中的差异[J]. 中国临床药理学与治疗学, 2011, 16(10): 1169-1173.

WANG Hai-bo, WU Shi-xiu, HUANG Qing-ke. Study on the methods of Chinese medicine and western medicine therapeutic evaluation for the treatment of advanced gastric cancer[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2011, 16(10): 1169-1173.

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