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中国临床药理学与治疗学 ›› 2012, Vol. 17 ›› Issue (5): 562-565.

• 药物治疗学 • 上一篇    下一篇

动脉化疗栓塞治疗晚期贲门癌临床观察

章俊, 谢亚敏, 武翠玲, 吴润琳, 吴克伟   

  1. 芜湖市第二人民医院肿瘤科,芜湖 241000,安徽
  • 收稿日期:2012-02-25 修回日期:2012-05-02 出版日期:2012-05-26 发布日期:2012-05-28
  • 作者简介:章俊,男,本科,主治医师, 研究方向:介入治疗技术在临床中的应用。Tel: 15955374478 E-mail: zhangjunjun75@sina.com

A clinical observation on the transarterial chemoembolization of advanced cardiac cancer

ZHANG Jun, XIE Ya-min, WU Cui-ling, WU Run-lin, WU Ke-wei   

  1. Department of Oncology ,the Second People's Hospital of Wuhu , Wuhu 241000,Anhui , China
  • Received:2012-02-25 Revised:2012-05-02 Online:2012-05-26 Published:2012-05-28

摘要: 目的:探讨动脉灌注化疗联合栓塞治疗晚期贲门癌的临床疗效。方法: 60例晚期贲门癌患者随机分为2组,即动脉灌注化疗联合栓塞组(治疗组,n=30)和静脉化疗组(对照组,n=30)。两组均采用相同化疗方案分别行动脉灌注化疗联合栓塞或静脉化疗,按WHO疗效评定标准评价近期疗效及观察患者临床症状改善情况。结果: 治疗组和对照组相比较,近期有效率显著增加(P<0.01),且临床症状改善明显。结论:动脉化疗联合栓塞治疗可以提高晚期贲门癌患者近期疗效并改善患者临床症状,可作为晚期贲门癌的一种有效治疗方法。

关键词: 贲门癌, 动脉灌注化疗, 栓塞治疗

Abstract: AIM: To investigate the clinical effects of the transarterial chemoembolization in the treatment of advanced cardiac cancer.METHODS: 60 patients with advanced cardiac cancer were randomly divided into 2 groups: the group combined arterial infusion chemotherapy with embolization (treatment group, n=30) and the intravenous chemotherapy group (control group, n=30).Patients in both groups were received same chemotherapy regimens. The recent effects of two treatment groups were evaluated according to the WHO criteria and the clinical symptom improvements were also observed.RESULTS:The response rate of treatment group was increased significantly (P<0.01) compared with the control group, and the clinical symptoms were improved significantly in treatment group.CONCLUSION: Combined arterial chemotherapy with embolization can improve the curative effects ,which can be used as an effective treatment in advanced cardiac cancer.

Key words: Cardiac cancer , Arterial perfusion chemotherapy , Embolism

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