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中国临床药理学与治疗学 ›› 2014, Vol. 19 ›› Issue (4): 430-436.

• 临床流行病学 • 上一篇    下一篇

芜湖市健康体检人群慢性肾脏疾病患病率及相关危险因素调查

杨沿浪1, 钟正灵2, 汪裕伟1, 高潮清1, 金岳龙3, 邹和群4   

  1. 1皖南医学院附属弋矶山医院肾内科,
    2临床药学部,
    3皖南医学院公共卫生系,芜湖 241000,安徽;
    4南方医科大学附属三院肾内科,广州 510630,广东
  • 收稿日期:2014-01-06 修回日期:2014-03-09 出版日期:2014-04-26 发布日期:2020-07-24
  • 通讯作者: 邹和群,通信作者,男,主任医师,教授,博士生导师,研究方向:慢性肾脏病流行病学、慢性肾脏病发病机制。Tel:13602825868 E-mail:Hequnzou@126.com
  • 作者简介:杨沿浪,男,主治医师,讲师,研究方向:慢性肾小球疾病及其发病机制。Tel:13855366863 E-mail:yangyanlang@126.com
  • 基金资助:
    EUFP7Program,UroSense(2011);安徽省高校自然科学研究基金(KJ2011Z384)

Prevalence and risk factors for chronic kidney disease in Wuhu

YANG Yan-lang1, ZHONG Zheng-ling2, WANG Yu-wei1, GAO Chao-qing1, JING Yue-long3, ZOU He-qun4   

  1. 1Department of Nephrology,
    2Institute of Clinical Pharmacology, Yijishan Hospital, Wannan Medical College,
    3Public Health Department of Wannan Medical College, Wuhu 241001, Anhui, China;
    4Department of Nephrology, Third Affiliated Hospital, Southern Medical University, Guangzhou 510630, Guangdong, China
  • Received:2014-01-06 Revised:2014-03-09 Online:2014-04-26 Published:2020-07-24

摘要: 目的: 调查芜湖市健康体检人群慢性肾脏病(CKD)患病率以及与CKD相关独立危险因素。方法: 40 377 名芜湖市健康体检居民(男性 24 164 名、女性 16 213 名)入选横断面研究。测量体质量、身高和血压,同时检测血常规、尿常规,血脂和肾功能,计算肾小球滤过率(eGFR)。结果: 芜湖市健康体检人群CKD流行率为 6.71%,男性高于女性(7.1% vs 5.0%)。蛋白尿、血尿及eGFR<60 mL·min-1·1.73 m-2 患病率分别为 1.83%、2.07%、3.4%,并随着年龄的增长而增长。多因素回归分析显示高尿酸血症、高血糖、贫血、年龄、性别及高血压为CKD相关独立危险因素[优势比(OR):2.28、1.70、1.65、1.48 和 1.29]。结论: 芜湖市城区人口CKD患病率低于国内其他研究报道,芜湖市人群CKD早期防治中要注意上述危险因素。

关键词: 慢性肾脏病, 患病率, 危险因素

Abstract: AIM: To investigate the prevalence and risk factors associated with chronic kidney disease (CKD) in Wuhu, China. METHODS: To investigate the prevalence and risk factors associated with chronic kidney disease (CKD) in Wuhu, China. RESULTS: The result showed the prevalence of CKD in Wuhu city was 6.71%. The prevalence of proteinuria, hematuria, and eGFR of less than 60 mL·min-1·1.73 m-2 were 1.83%, 2.07%, and 3.4% respectively, all of which were increased expectedly with age. multivariate analysis demonstrated hyperuricemia, diabetes, anemia, age,gemdre and hypertension (OR 2.28, 1.70, 1.65, 1.48, and 1.29, respectively) to be independent risk factors for CKD. CONCLUSION: CKD in Wuhu city is lower than the average CKD prevalence in China as a whole. The risk factors for CKD outlined above should considered as a potential strategy for the early identification and prevention of CKD.

Key words: chronic kidney disease, prevalence, risk factor

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