非酒精性脂肪肝与代谢综合征的临床相关性分析

中国临床药理学与治疗学 ›› 2014, Vol. 19 ›› Issue (6): 666-670.

非酒精性脂肪肝与代谢综合征的临床相关性分析

季学磊¹, 葛艺东², 安民民¹, 刘蕾¹, 丁俊¹, 解育新², 李春耘³

¹芜湖市第二人民医院内分泌科,
²超声科,
³健康管理中心, 芜湖 241000, 安徽

收稿日期:2014-05-08 修回日期:2014-06-18 发布日期:2014-07-01
作者简介:季学磊, 女, 硕士, 副主任医师, 研究方向:内分泌学。Tel: 0553-3839007 E-mail: 1370779310@qq.com
基金资助:
安徽省芜湖市科技惠民项目(2013hm38)

Correlation analysis between nonalcoholic fatty liver disease and metabolic syndrome

JI Xue-lei¹, GE Yi-dong², AN Min-min¹, LIU Lei¹, DING Jun¹, XIE Yu-xin², LI Chun-yun³

¹. Department of Endocrinology, Wuhu Second People's Hospital in Anhui Province, Wannan Medical Colleg；
².Department of Ultrasonography；3.Health management Center； Wuhu 241000, Anhui, China

Received:2014-05-08 Revised:2014-06-18 Published:2014-07-01

摘要/Abstract

摘要： 目的: 探讨非酒精性脂肪肝(NAFLD)与代谢综合征(MS)相关指标变化的关系, 并进行临床相关性研究。方法: 选择本院诊断的NAFLD患者共122例作为研究对象, 检测其酶学、代谢指标及并发症情况。结果: 与单纯NAFLD组比较, NAFLD合并MS组患者的BMI、TG、收缩压、舒张压、空腹血糖明显增高, 差异具有统计学意义(P＜0.05);血清总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及血尿酸差异无统计学意义(P>0.05);两组并发症之间差异具有统计学意义(P>0.05)。结论: NAFLD合并MS患者的代谢指标异常及并发症发生率高, 临床医师应重视, 并给与患者合理的建议。

关键词: NAFLD, MS, 并发症

Abstract: AIM : To investigate the correlation between nonalcoholic fatty liver disease(NAFLD) and metabolic syndrome (MS) by detecting the index of enzyme and metabolism. METHODS: 122 employees who receive physical examination in Physical Examination Center of the No'2 people' hospital of Wuhu were involved in the group, and the index of enzyme, metabolism, and complication were detected all of them. RESULTS:Compared with the pure NAFLD group, the levels of weight index, TG, systolic blood pressure, diastolic blood pressure and the fasting blood glucose in NAFLD with MS group were increased, there was statistically significant difference (P<0.05). the levels of TC, HDL-C, LDL-C, UA and the complications in two groups were similar, there was no statistically significant difference (P>0.05). CONCLUSION: The rate of abnormal index of metabolism and the complications of patients of NAFLD with MS were higher, and physician should pay attention to it and give some suggestion about it to patients of NAFLD with MS.

Key words: nonalcoholic fatty liver disease , metabolic syndrome, complication

中图分类号:

R575.5

季学磊, 葛艺东, 安民民, 刘蕾, 丁俊, 解育新, 李春耘. 非酒精性脂肪肝与代谢综合征的临床相关性分析[J]. 中国临床药理学与治疗学, 2014, 19(6): 666-670.

JI Xue-lei, GE Yi-dong, AN Min-min, LIU Lei, DING Jun, XIE Yu-xin, LI Chun-yun. Correlation analysis between nonalcoholic fatty liver disease and metabolic syndrome[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(6): 666-670.

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