门诊精神分裂症患者药物治疗的依从性与不良反应、社会支持的关系

中国临床药理学与治疗学 ›› 2014, Vol. 19 ›› Issue (8): 912-915.

门诊精神分裂症患者药物治疗的依从性与不良反应、社会支持的关系

杭荣华¹, 李业平², 吴明飞², 李瑞²

¹ 皖南医学院心理学教研室,芜湖 241002,安徽;
² 芜湖市第四人民医院精神科,芜湖 241006,安徽

收稿日期:2013-12-04 修回日期:2014-07-03 出版日期:2014-08-26 发布日期:2014-08-26
作者简介:杭荣华,女,硕士,副教授,研究方向:精神障碍的心理治疗、神经心理学。 Tel: 13033033593 E-mail: rhhang311@126.com
基金资助:
2012年皖南医学院重点科研项目培育基金(WK2012Z04); 教育部人文社会科学研究规划基金项目(2013YJA840005)

Relationship on medication compliance, antipsychotic side-effects and social support in schizophrenia outpatients

HANG Rong-hua¹, LI Ye-ping², WU Ming-fei², LI Rui²

¹ Department of Psychology, Wannan Medical University, Wuhu 241002, Anhui, China;
² Department of Psychiatry, the Fourth People's Hospital, Wuhu 241006, Anhui, China

Received:2013-12-04 Revised:2014-07-03 Online:2014-08-26 Published:2014-08-26

摘要/Abstract

摘要： 目的探讨门诊精神分裂症患者药物治疗的依从性与抗精神病药物不良反应、社会支持的关系。方法 132例精神分裂症患者完成药物副反应量表(TESS)、社会支持评定量表(SSRS)、药物治疗依从性问卷,分析影响依从性的相关因素。结果 ①患者药物治疗依从性评分为(9.45±1.29)分;不同婚姻、医保、工作状况患者的依从性有显著差异:离异者的依从性低于未婚和已婚者;有医保者依从性高于无医保者;有固定工作或收入者高于无固定工作或收入者(P<0.05);②依从性评分与TESS总均分呈负相关(r=-0.727),与社会支持总分呈正相关(r=0.369) ;③TESS总均分对依从性有负向预测作用,而社会支持对依从性有正向预测作用。结论抗精神病药的不良反应和社会支持是影响门诊分裂症患者依从性的重要因素,需采取合理的应对措施。

关键词: 精神分裂症, 抗精神病药, 依从性, 不良反应, 社会支持

Abstract: AIM: To explore the relationship on medication compliance, antipsychotic drugs side-effects and social support in schizophrenia outpatients. METHODS: 132 schizophrenia outpatients were were evaluated with Treatment Emergent Symptom Scale(TESS), Social Support Rating Scale (SSRS) and Medication Compliance Scale. The related factors influencing the medication compliance were analyzed. RESULTS: ①The score of Medication Compliance Scale was (9.45±1.29). There were significant differences on Medication Compliance Scale score among different marital state, health insurance and working position. Score of the divorced was lower than unmarried or married patients, patients with health insurance was higher than those without medical insurance, and patients who have a job was higher than have no job. ②Compliance Scale score was significantly negative correlation with TESS (r=-0.727), significantly positive correlation with SSRS (r=0.369). ③Multi-regression showed, TESS Score forecasted compliance negatively. Score of SSRS forecasted compliance positively. CONCLUSION: Antipsychotic drugs side-effect and social support are important factors for medication compliance. Reasonable measures should be taken.

Key words: schizophrenia, antipsychotics, compliance, side-effect, social support

中图分类号:

R749

杭荣华, 李业平, 吴明飞, 李瑞. 门诊精神分裂症患者药物治疗的依从性与不良反应、社会支持的关系[J]. 中国临床药理学与治疗学, 2014, 19(8): 912-915.

HANG Rong-hua, LI Ye-ping, WU Ming-fei, LI Rui. Relationship on medication compliance, antipsychotic side-effects and social support in schizophrenia outpatients[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(8): 912-915.

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