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中国临床药理学与治疗学 ›› 2017, Vol. 22 ›› Issue (11): 1315-1320.

• 综述与讲座 • 上一篇    

胃肠间质瘤临床诊治现状与进展

何 苗1,范 晶2,王子卫3,赵和照1   

  1. 1重庆市肿瘤研究所胃肠外科,重庆大学附属肿瘤医院,重庆 400030; 2重庆医科大学附属第一医院急诊科,重庆 400016; 3重庆医科大学附属第一医院普通外科,重庆 400016
  • 收稿日期:2017-04-06 修回日期:2017-06-18 出版日期:2017-11-26 发布日期:2017-12-11
  • 通讯作者: 赵和照,男,本科,副主任医师,研究方向:胃肠道肿瘤基础与临床。 Tel:13608369620 E-mail:zhzalee@163.com
  • 作者简介:何苗,男,博士,主治医师,研究方向:胃肠外科基础与临床。 Tel:13996123692 E-mail:hemiao7777777@163.com

Progress of diagnosis and therapy on gastrointestinal stromal tumors

HE Miao 1, FAN Jing 2, WANG Ziwei 3, ZHAO Hezhao 1   

  1. 1 Department of Gastrointestinal Surgery, Chongqing Cancer Institute,ChongQing University Cancer Hospital, Chongqing 400030, China; 2 Department of Emergency,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China; 3 Department of General Surgery,the first Affiliated Hospital of Chongqing Medical University, Chongqing 400016,China
  • Received:2017-04-06 Revised:2017-06-18 Online:2017-11-26 Published:2017-12-11

摘要:

胃肠间质瘤(gastrointestinal stromal tumors,GISTs)是临床常见的间叶细胞来源肿瘤,目前对其发病机制的理解已明显促进其临床诊治进展,甚至该肿瘤的诊治已成为肿瘤多学科联合诊疗领域的典范。本文综述GIST临床诊治现状与进展,包括病理诊断、手术治疗与药物治疗方面,以期为临床医师提供参考。

关键词: 胃肠间质瘤, 诊断, 治疗, 进展, 酪氨酸激酶抑制剂

Abstract:

Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors originating in the gastrointestinal tract. The understanding of GIST's pathogenesis improves the clinical diagnosis and treatment of this disease. And the diagnosis and treatment of GIST becomes the model of tumor multidisciplinary treatment. This article summarizes the progress of diagnosis and treatment of GIST, including the pathology, surgery and drug therapy. We hope this overview can help clinical doctors to treat GIST patients better.

Key words: GIST, diagnosis, therapy, progress, TKI

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