关键词: 中医化痰法, 非小细胞肺癌, 免疫功能, 生活质量, Meta分析

Abstract:

AIM: To systematically evaluate the efficacy of reducing phlegm with traditional Chinese medicine on non-small cell lung cancer. METHODS: We retrieved randomized controlled trials of efficacy of reducing phlegm with traditional Chinese medicine on non-small cell lung cancer from database of CNKI, WANFANG, VIP, PubMed that published since 2000. Three hundred and twenty-four patients treated by reducing phlegm with traditional Chinese medicine and chemotherapy were included in the experimental group; while another 323 patients treated by sole chemotherapy were included in the control group. All patients were selected then according to the including and excluding standard so as to evaluate the quality of literature. Experimental results were analyzed by STATA11.0 statistics software. RESULTS:A  total of 647 cases of non-small cell lung cancer patients were included, with 324 cases in the experimental group and 323 cases in the control group. Phlegm reducing therapy presented elevated effective rate (RR=1.48, 95%CI=1.24 to 1.77, P<0.001); improved life quality (RR=1.92,95%CI=1.51 to 2.45, P<0.001); and better immunity (MD=0.36，95%CI=0.23 to 0.50, P<0.001). CONCLUSION: Compared with conventional medicine, reducing phlegm with traditional Chinese medicine exhibit better effect on non-small cell lung cancer.

Key words: reducing phlegm with traditional Chinese medicine, non-small cell lung cance, immunity,  living quality, Meta-analysis