关键词: 垂体后叶素, 卵巢子宫内膜异位囊肿, 卵巢储备功能

Abstract:

AIM: To observe the application effect of vasopressin used in laparoscopic cystectomy of ovarian endometriosis cyst. METHODS: One hundred and four patients with ovarian endometriosis cyst were randomly divided into two groups,the observation group(the operation was using vasopressin before laparoscopic cystectomy) and control group (routine laparoscopic cystectomy) 52 cases in each group.The operation time,blood loss,cyst rupture rate,postoperative body temperature,anal exhaust time and the levels of follicle-stimulating hormone (FSH), luteinizing hormone(LH),estradiol (E2) at the preoperative and postoperative one month were observed between two groups. RESULTS: Operation time,blood loss,cyst rupture rate of observation group were less than those of control group,the difference were statistically significant (P<0.05).Compared with preoperative,the postoperative one month (7.17±1.27),three month(7.13±1.26),six month(7.12±1.32) levels of FSH in observation group were slightly higher,there was no statistically difference(P>0.05);the postoperative one month(186.67±34.16) level of E2 in observation group was slightly reduced,and three month (193.56±31.46),six month(204.79±33.48) levels of E2 were gradually rised,there was no statistically difference(P>0.05).In control group,the postoperative one month (7.91±1.16),three month(7.48±1.44),six month(7.22±1.60) level of FSH were higher than the preoperative level, the difference were statistically significant (P>0.05); and the postoperative one month(171.35±28.75),three month(179.42±27.64), six month(180.31±29.04) levels of E2 were lower than the preoperative level,although the three month and six month were slightly higher than one month,compared with preoperative there was significant difference (P<0.05). Compared with preoperative,two groups of postoperative one month,three months, six months levels of LH showed no statistically significant difference (P>0.05). CONCLUSION: Using vasopressin before laparoscopic cystectomy can shorten the operation time, decrease blood loss and cyst rupture rate,and is helpful to protect ovarian reserve function, which worth promoting in clinical.

Key words: vasopressin, ovarian endometriosis cyst, ovarian reserve function