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中国临床药理学与治疗学 ›› 2021, Vol. 26 ›› Issue (10): 1174-1180.doi: 10.12092/j.issn.1009-2501.2021.10.010

• 综述与讲座 • 上一篇    下一篇

中药连花清瘟胶囊/颗粒在呼吸系统疾病中的药理研究及临床应用进展

尹玉洁,常丽萍   

  1. 络病研究与创新中药国家重点实验室,国家中医药管理局重点研究室(心脑血管络病),河北省中西医结合医药研究院,石家庄 050035,河北
  • 收稿日期:2021-04-27 修回日期:2021-08-06 出版日期:2021-10-26 发布日期:2021-11-02
  • 通讯作者: 常丽萍,通信作者,女,博士,主治医师,研究方向:中医心肺疾病。Tel: 0311-85040752 E-mail: changliping@yiling.cn E-mail:changliping@yiling.cn
  • 作者简介:尹玉洁,女,博士,主治医师,研究方向:中医心肺疾病。Tel: 0311-85040752 E-mail: yinyujieyyj@163.com
  • 基金资助:
    国家重大新药创制专项(2018ZX09737002);国家自然科学基金重点项目(82130123);中央引导地方科技发展资金项目(科技创新基地项目)(206Z2503G)

Pharmacological research and clinical applications progress of Lianhua Qingwen capsules/granules in respiratory diseases

YIN Yujie,CHANG Liping   

  1. State Key Laboratory of Collateral Disease Research and Innovative Chinese Medicine Medicines, Key Laboratory of National Administration of Traditional Chinese Medicine (Cardiovascular & Cerebrovascular Collateral Disease), Hebei Institute of Integrated TCM and Western Medicine, Shijiazhuang 050035, Hebei, China
  • Received:2021-04-27 Revised:2021-08-06 Online:2021-10-26 Published:2021-11-02

摘要: 连花清瘟胶囊/颗粒是应用中医络病理论指导研制的治疗感冒、流行性感冒的创新中药,具有“清瘟解毒、宣肺泄热”功能。2003年严重急性呼吸综合征(SARS)期间通过中国国家药品监督管理局药品快速审批通道获批,现已成为治疗呼吸系统传染性疾病的代表性中成药。连花清瘟药效学研究显示出具有广谱抗病毒,抑菌抗炎,退热、止咳、化痰,调节免疫等作用,临床应用于新型冠状病毒肺炎、流行性感冒、上呼吸感染、肺部感染、慢性阻塞性肺疾病急性加重等多种呼吸系统传染性及感染性疾病并取得显著疗效。

关键词: 连花清瘟, 呼吸系统疾病, 新冠肺炎, 流感, 肺部感染, 中医药

Abstract: Lianhua Qingwen capsules/granules is an innovative Chinese medicine developed under the guidance of the TCM collateral disease theory. It has the efficacy of "clearing heat and removing toxin, ventilating the lungs and discharging heat". In 2003, it was approved as a new drug by the China National Medical Products Administration, through expedited approval during/SARS, and now, it has become a representative proprietary Chinese medicine for the treatment of infectious diseases of the respiratory system. Pharmacodynamic studies have revealed that LianhuaQingwen has broad-spectrum antiviral, antibacterial and anti-inflammatory, antipyretic, cough-relieving and immunoregulation effects. Clinically it has been used in the treatment of communicable and infectious respiratory diseases such as COVID-19, influenza, upper respiratory infection, pulmonary infections, acute exacerbation of chronic obstructive pulmonary disease, etc. and has achieved remarkable curative effects.

Key words: Lianhua Qingwen, respiratory diseases, COVID-19, influenza, pneumonia, traditional Chinese medicine

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