“卫气营血”理论辨证防治急性肺损伤研究现状

doi:10.12092/j.issn.1009-2501.2023.04.010

中国临床药理学与治疗学 ›› 2023, Vol. 28 ›› Issue (4): 429-437.doi: 10.12092/j.issn.1009-2501.2023.04.010

“卫气营血”理论辨证防治急性肺损伤研究现状

齐晓风1，骆亚莉1,2，肖孟勇1，周世琴1，周雯1，安方玉1，魏本君1，刘永琦1,2

1甘肃中医药大学，甘肃省高校重大疾病分子医学与中医药防治研究省级重点实验室，甘肃 730000，兰州；2甘肃中医药大学，甘肃省中医药防治慢性疾病重点实验室，甘肃 730000，兰州

收稿日期:2022-12-07 修回日期:2023-01-30 出版日期:2023-04-26 发布日期:2023-05-17
通讯作者: 骆亚莉，女，博士，副教授，研究方向：中西医结合防治炎症免疫性疾病研究。 E-mail: mailoflyl@126.com
作者简介:齐晓风，女，硕士，研究方向：肺系疾病的中西医结合防治基础研究。 E-mail: 776255509@qq.com
基金资助:
国家自然科学基金（82160846），甘肃省科技厅自然科学基金项目（20JR10RA321），甘肃省教育厅高等学校创新基金（2021A-085），甘肃省“双一流”科研重点项目（GSSYLXM-05）

Research status of dialectical prevention and treatment of acute lung injury based on the theory of "Wei qi and Ying Xue"

QI Xiaofeng1, LUO Yali1,2, XIAO Mengyong1, ZHOU Shiqin1, ZHOU Wen1, AN Fangyu1, WEI Benjun1, LIU Yongqi1,2

1Gansu University of Chinese Medicine, Provincial Key Laboratory of Molecular Medicine and TCM for the Prevention and Treatment of Major Diseases in Colleges and Universities of Gansu Province, Gansu 730000, Lanzhou, China; 2Gansu University of Chinese Medicine, Key Laboratory of Chronic Diseases for Prevention and Treatment of Traditional Chinese Medicine of Gansu Province, Gansu 730000, Lanzhou, China

Received:2022-12-07 Revised:2023-01-30 Online:2023-04-26 Published:2023-05-17

摘要/Abstract

摘要： 急性肺损伤（ALI）是临床常见危重型呼吸系统疾病。目前该病机制尚未完全阐明，临床上缺乏特效药且致死率高，是医学领域的难题。近年来，传统中医药在防治ALI发挥出其独特的优势和功效，引起国内外学者关注。本文基于“卫气营血”理论探讨中医药防治ALI 的研究现状，就其发病机制、临床表现等与中医病证对应分析。研究发现按“卫气营血”角度展开辨证论治，其发病进展与免疫应答、炎症反应、氧化应激和细胞凋亡等环节高度一致，可为临床中西医结合防治ALI寻找新的思路与用药。

关键词: 急性肺损伤, 卫气营血, 中医药, 暴喘

Abstract:

Acute lung injury (ALI) is a common clinical critical respiratory disease. At present, the mechanism of the disease has not been fully elucidated, there is a lack of specific drugs in clinical practice and the mortality rate is high, which is a difficult problem in the medical field. In recent years, traditional Chinese medicine has exerted its unique advantages and efficacy in the prevention and treatment of ALI, which has aroused the attention of domestic and foreign scholars. Based on the theory of "Wei Qi Ying Xue", this paper discusses the current research status of prevention and treatment of ALI by traditional Chinese medicine, and analyzes its pathogenesis, clinical manifestations and corresponding analysis with TCM syndrome. According to the angle of "Wei Qi Ying Xue", the progress of syndrome differentiation and treatment is highly consistent with immune response, inflammatory response, oxidative stress and apoptosis, in order to find new ideas and medication for the prevention and treatment of ALI with integrated traditional Chinese and Western medicine.

Key words: acute lung injury, Wei Qi Ying Xue, traditional Chinese medicine, wheezing

中图分类号:

R563
R28

齐晓风, 骆亚莉, 肖孟勇, 周世琴, 周雯, 安方玉, 魏本君, 刘永琦. “卫气营血”理论辨证防治急性肺损伤研究现状[J]. 中国临床药理学与治疗学, 2023, 28(4): 429-437.

QI Xiaofeng, LUO Yali, XIAO Mengyong, ZHOU Shiqin, ZHOU Wen, AN Fangyu, WEI Benjun, LIU Yongqi. Research status of dialectical prevention and treatment of acute lung injury based on the theory of "Wei qi and Ying Xue"[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2023, 28(4): 429-437.

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“卫气营血”理论辨证防治急性肺损伤研究现状

Research status of dialectical prevention and treatment of acute lung injury based on the theory of "Wei qi and Ying Xue"

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