关键词: 早孕, 药物流产, 人工流产, 药物联合人工流产

Abstract: Aim To compare the advantage of different methods of terminating early pregnancy. Methods 684 women in early pregnancy(≤49 d)were allocated into three groups according to their request:Group A (medical abortion, n=241), taking (po)mifepristone 25 mg every 12 h for three days and then taking misopostol 600 μg at 8:00 on the forthday;Group B (induced abortion, n=220), taking the routine intrauterine operation by vacuum aspirator and Group C (medical with induced abortion, n=223), inserting a Gongshuan suppository into rectum 0.5 ~ 2 h before induced abortion operation.Some indices w ere compared, including the efficacy, vaginal bleeding volume and time, side effects and acceptability of the three abortion methods.Results The abortion effects of Group C and B are better than that of Group A (P<0.01).The vaginal bleeding volume of Group C is the least, then is the Group B, and the last is Group A (P<0.01).The vaginal bleeding time of Group B and C is apparently shorter than that of Group A (P<0.01).The infection rate after abortion operation of Group B and C is lower, compared with Group A (P<0.01, P<0.05).The acceptability rate of medical with induced abort ion is higher than that of the other two groups (P<0.01).Conclusion The medical with induced abortion is a safe, fast, less painful and less side effects approach to terminate early pregnancy, and it is easily accepted by patients.

Key words: early pregnancy, medical abortion, induced abortion, medical with induced abortion