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中国临床药理学与治疗学 ›› 2013, Vol. 18 ›› Issue (3): 322-324.

• 药物治疗学 • 上一篇    下一篇

CO2激光联合ALA光动力疗法治疗肛周复发性尖锐湿疣的疗效观察

王军, 刘雯蓓, 慈超, 常小丽, 何彩凤, 强娣, 杭守云, 季必华   

  1. 皖南医学院弋矶山医院皮肤科,芜湖 241001,安徽
  • 收稿日期:2012-07-06 修回日期:2012-11-05 出版日期:2013-03-26 发布日期:2013-04-02
  • 作者简介:王军,男,副主任医师,讲师,研究方向:为皮肤性病方向。E-mail: 1813wj@163.com
  • 基金资助:
    安徽高校省级自然科学研究基金项目(KT2013B324)

Clinical observation of CO2 laser combined with ALA photodynamic therapy for recurrent perianal Condyloma Acuminatum

WANG Jun, LIU Wei-bei, CI Chao, CHANG Xiao-li, HE Cai-feng, QIANG Di, HANG Shou-yun, JI Bi-hua   

  1. Department of Dermatology, Yijishan Hospital of Wannan Medical College, Wuhu 241001, Anhui,China
  • Received:2012-07-06 Revised:2012-11-05 Online:2013-03-26 Published:2013-04-02

摘要: 目的: 探讨CO2激光联合ALA光动力疗法治疗肛周复发性尖锐湿疣的疗效。方法: 肛周复发尖锐湿疣患者46例,随机分为2组。治疗组为CO2激光联合ALA光动力,先用CO2激光祛除疣体,再采用光动力激光治疗仪对患处行照光治疗,每周一次,连续3次;对照组为CO2激光治疗组,以目视下疣体完全清除。治疗后第1周进行疗效评价,在治疗后3个月内对患者进行随访以评价复发率。结果: 两组患者治疗后疣体均完全消失;治疗组复发率为19%,对照组复发率为65%,安全性好。结论: CO2激光联合ALA光动力疗法治疗肛周复发性尖锐湿疣安全有效,能降低复发率。

关键词: 尖锐湿疣, 氨基酮戊酸, 光动力疗法

Abstract: AIM: To investigate the efficacy of CO2 laser combined with ALA photodynamic therapy for recurrent perianal Condyloma Acuminatum.METHODS: Forty-six patients with perianal Condyloma Acuminatum were randomly divided into two groups, experimental group for the CO2 laser combined with ALA photodynamic therapy (ALA-PDT), first with CO2 laser dispel wart body, exposing out photodynamic laser treatment, once a week for three consecutive times; control group for the CO2 laser treatment group, visually the wart was completely cleared.One week after the treatment for efficacy evaluation,all patients were followed up to evaluate the recurrence rate within 3 months after treatment.RESULTS: After treatment, the warts were completely disappear, the recurrence rate of experimental group and control group was 19%,65%,respectively.CONCLUSION: CO2 laser combined with ALA photodynamic therapy for recurrent perianal Condyloma Acuminatum is safely and effectively, can reduce the relapse rate.

Key words: Condyloma acuminatum, Aminolevulinic acid hydrochloride, Photodynamic therapy

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