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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2017, Vol. 22 ›› Issue (5): 565-569.

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Chemotherapy compliance of patients with digestive system cancer and its influencing factors

LI Xiu 1, JI Zhaoning 2   

  1. 1 Department of Psychology, Wannan Medical College, Wuhu 241002, Anhui,China; 2 Department of Oncology, Yijishan Hospital, Wannan Medical College, Wuhu 241000, Anhui, China
  • Received:2017-02-16 Revised:2017-03-27 Online:2017-05-26 Published:2017-05-27

Abstract:

AIM: To investigate the relationship between the chemotherapy compliance and general status, symptoms of chemotherapy, emotional experience and resilience of patients with digestive system cancer.  METHODS: The Connor-Davidson Resilience Scale (CD-RISC), MD Anderson Symptom Inventory (MDASI) and chemotherapy compliance questionnaire were used to assess the 165 digestive system cancer patients. RESULTS:The score of chemotherapy compliance was (15±7) points, which was influenced by such factors as age of patients, mode of payment and participation in exercise (P<0.05). Score of chemotherapy compliance was significantly positively correlated with score of MDASI (r=0.812), while significantly negatively correlated with CD-RISC (r=-0.177). The scores of CD-RISC and MDASI as well as two factors of MDASI were applied to the multiple regression equation. CONCLUSION:Patient's symptoms during chemotherapy, emotional experience and resilience are important factors influencing chemotherapy compliance. Medical staff and relevant departments are required to take effective measures to improve the chemotherapy compliance of patients.

Key words: digestive system cancer, chemotherapy compliance, resilience, MD Anderson Symptom

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