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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2019, Vol. 24 ›› Issue (1): 111-115.doi: 10.12092/j.issn.1009-2501.2019.01.019

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Research progress of fibroblast growth factor 1 in the treatment of diabetes and related diseases

JIN Hui 1, ZHOU Ziye 1, LIANG Jing 1, WANG Chenxiang 1, SONG Lintao 2, ZHAO Longwei 2, GUO Kaiwen 2   

  1. 1 Department of Pharmacy of the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China; 2 School of Pharmacy of Wenzhou Medical University, Wenzhou 325000, Zhejiang, China
  • Received:2018-07-22 Revised:2018-08-25 Online:2019-01-26 Published:2019-01-25

Abstract:

Acid fibroblast growth factor (FGF-1) as found earlier as an important member of fibroblast growth factor family, which stimulates the growth of blood vessels, accelerate wound healing and promote nerve injury repair has been widely recognized before,in recent years, research on the potential biological function of it in endocrine system has become a hot point. This article will review the FGF-1 about structure, function, receptor signaling pathway and treatment of diabetes and related diseases.

Key words: fibroblast growth factor 1, diabetes

CLC Number: