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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2007, Vol. 12 ›› Issue (7): 835-837.

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Clinical efficacy and safety evaluation of Jianweiyuyangpian in treatment of 314 patients with peptic ulcer

LIANG Xiao-qing1, DING Hong-ming2, LI Ai-guo3, CHANG Sheng4, WANG Xian-guo5, HE Jun6, ZHAO Yi7   

  1. 1Department of Pharmacy, 2Department of Traditional Chinese Medicine, Zhongda Hospital, Southeast University, Nanjing 210009, J iangsu, China;
    3Department of Traditional Chinese Medicine, Inner Mongolia Autonomous Region Hospital, Hohhot 010000, InnerMongolia, China;
    4Department of Tumor, Shaoxing Hospital of Traditional Chinese Mediche, Shaoxing 312000, Zhejiang, China;
    5Department of Coction Anabrosis, Changzhou Hospital of Traditional Chinese Mediche, Changzhou 213000, Jiangsu, China;
    6Department of Coction Medical, Dean Hospital of Changzhou, Changzhou 213003, Jiangsu, China;
    7Department of Tumor, 454th Hospital of PLA, Nanjing 210002, Jiangsu, China
  • Received:2007-06-18 Revised:2007-07-12 Online:2007-07-26 Published:2020-10-27

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Abstract: AIM: To evaluate the clinical efficacy and safety of Jianweiyuyangpian in the treatment of 314 patients with peptic ulcer. METHODS: 446 patients with peptic ulcerwere randomly divided into two groups of treatment group and control group.314 patients in treatment group were administered with Jianweiyuyangpian orally and 132 patients in control group with ranitidine capsules for 4 weeks. RESULTS: After treating for 4 weeks the ulcer cure rate, efficacy rate, six month recurance rate, pain relief rate and pain disappearance rate of treatment group were 59.87%, 91.40%, 12.24%, 93.00% and 79.33% respectively, while those of control group were 58.33%, 89.39%, 14.04%, 88.46% and 72.30% respectively.The differences between two groups were not significant (P>0.05).Both of the two groups had no adverse event. CONCLUSION: Jianweiyuyangpian is a safe and effective drug for treating peptic ulcer.

Key words: Jianweiyuyangpian, ranitidine, peptic ulcer, clinical efficacy, safety

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