A Meta analysis on the effectiveness and safety of Mailuoning injection on cerebral infarction system

Abstract

Abstract: AIM: To evaluate the effectiveness and safety of Mailuoning injection on cerebral infarction system. METHODS: A systematic review of randomized controlled trials (RCT)of Mailuoning injection on cerebral infarction system was performed.Trials were identified by searching the Cochrane Library (issue 12, 2008),MEDL I NE (1966-2008), BMBASE (1984-2008) and CNKI (1979-2008).Two authors assessed the quality and reviewed the data independently.Statistical analysis was performed by using Rev Man 5.0.17.0. RESULTS: Thirteen trials ranked high quality were included.Meta-analysis of the treatment of Mailuoning injection on cerebral infarction system showed there were no significant differences between Mailuoning injection and the control group [OR 0.72, 95%CI 0.47 to 1.11), P=0.23].No serious systematical adverse reaction was recorded in the two trails. CONCLUSION: Mailuoning injection is an more effective and safe regimen for the treatment of cerebral infarction system than control group probably, but not certain.

Key words: Mailuoning injection, Meta analysis, cerebral infarction, randomized controlled trials

CLC Number:

R911
R969

SHI Qing-ping, DING Feng, ZHU Jin-xiu, CHENG Peng, XU Shan-chu, LIU Yan. A Meta analysis on the effectiveness and safety of Mailuoning injection on cerebral infarction system[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2009, 14(6): 650-654.

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