Abstract: AIM: To observe the effects of Taizih'an in reducing the hyperlipidemia in rabbit models and to explore the mechanisms.METHODS: Hypelipidemia animal models were set upby normal diet and high choleisterol diet in rabbits.The concentrations of lipoprotein lipase and transaminase were detected by full automatic biochemical instrument.The fomation of plaque in the aorta was observed by staining with oil red O.RESULTS: Taizih'an obviously reduced the concentration of serum triglyeride and increased the content of lipoprotein lipase and high density lipoprotein.Taizhi'an had no obvious influence in the hepatic function.CONCLUTION: Taizhian can decrease the hyperlipidemia.Its mechanism is related to regulation of lipid metabolism and improvement of the concentration of lipoprotein lipase.

Key words: Taizhian, hyperlipidemia model, lipoprotein lipase, transaminase