Abstract: AIM: To investigate the hemostatic effect of fully hemostatic fibre (FHF).METHODS: In the animal experiment, 30 rabbits were treated to produce different models of trauma surface and artery and vein trauma.Different materials were used to stopbleeding, in order to compare the hemostasis time and the bleeding volume and observe the difference of hemostatic effect for different materials between before and after the treatment with heparin.A prospective study was designed.Two hundred and fourteen patients admitted in our department due to surgery were divided randomly into test groupand control group.FHF was used in test groupand Glutin Spong and vaseline oil gauze in the control groups for hemostasis with a view to comparing their hemostasis time and effect.RESULTS: It was suggested that the hemostatic effect of FHF had no significant difference with the Surgicel group.FHF and Surgicel groups appeared significant difference with the Glutin Sponge (p<0.05).No significant difference by using FHF was observed between before and after the treatment with heparin, but significant difference (p<0.05) was found in the Glutin Sponge.The results of clinical test suggested that the hemostatic time of FHF was shorter than that of control group.CONCLUSION: The results of animal experiment and clinical test demonstrated that the hemostatic effects of FHF were not only believable, but also safety and convenience.

Key words: fully soluble hemostatic fibre, animal trial, clinic test, trauma model, hemostatic effects