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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2006, Vol. 11 ›› Issue (3): 241-245.

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Applications of antisense oligonucleotides in cardicvascular disease

GAO Ping, SHI Gang-gang   

  1. Department of Pharmacology,Medical College,Shantou University,Shantou 515041,Guangdong,China
  • Received:2006-01-02 Revised:2006-01-20 Online:2006-03-26 Published:2020-12-04

Abstract: Antisense oligonucleotides is applicated abroadly in cardiovascular disease.It aims at the target genes involved in molecule mechanisms of disease pathogenesis.This technology reveals good foreground as a kind of clinical drug because of its researchful and therapeutic function in hypertension 、coronary disease,complications of heart transplantation and failure.

Key words: antisense oligonucleotides, cardiovascular disease, hypertension, coronary dise-ase, heart transplantation, heart failure

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