AIM: To display the distribution of evidence in the field of Yiqifumai injection treatment for heart failure. METHODS: To retrieve relevant databases such as CBM, CNKI, Wanfang, VIP, Cochrane Library, PubMed, Embase, and Web of Science, and search for the China Clinical Trial Registry, ClinicalTrials.gov and collect clinical studies, systematic evaluations, and guideline studies on the treatment of heart failure with Yiqifumai injection. The evidence map research method use a table to display the proportion of literature, sample size, comorbidities, and quality evaluations of systematic evaluations. Use a pie chart to display the proportion distribution of research types, a line chart to describe publication trends, and a bubble chart to display the distribution of evidence. RESULTS: The overall number of articles on the treatment of heart failure with Yiqifumai injection is in a steady development stage. Clinical studies are mainly small sample, single center, short-term randomized controlled trials, with a sample size of 60-100 cases and an intervention duration of mostly 14 days. The underlying disease is mainly coronary heart disease. Clinical research evidence tends to support the therapeutic effect of Yiqifumai injection combined with conventional Western medicine in improving heart failure patients' heart function and quality of life. However, there are also issues such as low overall quality of research, unreasonable clinical trial design, small sample size, incomplete selection of outcome indicators, low international recognition of certain outcome indicators, and lack of reporting on long-term outcomes The overall quality of randomized controlled trials andsystematic evaluation methodology is low. CONCLUSION: In the future, more large sample, multicenter clinical randomized controlled trials should be conducted to obtain higher-level evidence-based medicine evidence to fully demonstrate the advantages of traditional Chinese medicine treatment, and promote the common development of traditional Chinese medicine cardiology and evidence-based medicine.