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Chinese Journal of Clinical Pharmacology and Therapeutics ›› 2011, Vol. 16 ›› Issue (9): 1026-1029.

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Radiofrequency ablation of premature ventricular contractions with ECG like originating from the right ventricular outflow tract guided by CARTO

JI Yuan, DING Zhi-jian, JIANG Jian-guang, LIU Zhi-ping, ZHOU Xue-jun   

  1. Department of Cardiology, Changzhou No.2 People's Hospital Affiliated to Nanjing Medical University, Changzhou 213000, Jiangsu, China
  • Received:2011-08-10 Revised:2011-09-05 Online:2011-09-26 Published:2011-10-11

Abstract: AIM: To assess the clinical efficacy of electro-anatomically guided mapping and radiofrequency ablation under CARTO system for frequent premature ventricularcontraction. METHODS: The CARTO electro-anatomical mapping system displays real time three dimensional chamber structure with electrical information related to signal mplitude and activation time. 22 patients with Drug refractory and frequent premature ventricular contractions were ablated under CARTO system. By preoperative and postoperative SF-36, the generally health, physical function and conduct scoring among patients after procedure were observed. RESULTS: Frequent premature ventricular contractions were successfully ablated in all 22 patients with mean 2.6±1.2 radiofrequency applications under CARTO system. 19/22 frequent premature ventricular contractions occurred in right ventricle, and 3/22 in left ventricule. After ablation, the premature ventricular contractions declined from (17932±3816) beats/24 h to (13±6) beats/24 h, and patient's symptoms almost disappeared. No recurrent case was found during following observation. The patient overall quality of life improved markedly. CONCLUSION: The CARTO electro-anatomical mapping system, referred to the electro physiologic data, may be applied in guiding the radiofrequency ablation of drug-refractory and frequent premature ventricular contractions in those patients who have no organic heart disease for its highly efficacy, safety and accurate orientation, and could significantly improve patient quality of life.

Key words: Premature ventricular contractions, Ventricular tachycardia, Catheter ablation, CARTO system, Electro-anatomic mapping, SF-36, Quality of life

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