Meta-analysis: efficacy and safety of asarone on asthmatic bronchitis

Abstract

Abstract: AIM: To evaluate the efficacy and safety of asarone injection on asthmatic bronchitis. METHODS: The databases were retrieved from CNKI, VIP, CBM, PubMed,Chinese Technologic Journal Database (Weipu) and Wan Fang Digital Journal Full-text Database(before September 2012). The clinical researches about asarone injection in treating asthmatic bronchitis were collected to evaluate the clinical efficacy and safety by meta-analysis.RESULTS: 19 studies were included.The total effective rate of asarone group was higher than that of control group [OR=4.3 and 95%CI =(3.05,6.08),Z=8.3,P<0.00001].And all of other secondary outcome measures of asarone group including cough days, asthma days, wheeze disappeared time, chest X-ray back to normal time, hospital days were better than those of control group, the difference was statistically significant. Safety of asarone injection could not be evaluated because of the information was limited.CONCLUSION: Asarone injection is effective in the treatment of asthmatic bronchitis.

Key words: Asarone injection, Meta-analysis, Asthmatic bronchitis

CLC Number:

R311

XU Zhe, CHEN Qun, PU Zhi-chen, HU Hua, XIE Hai-tang. Meta-analysis: efficacy and safety of asarone on asthmatic bronchitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2013, 18(1): 39-45.

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