Abstract: AIM: To calculate sample size and power of measurement data in non-inferior trials using SAS programming. METHODS: Two calculation method, formula and SAS programming, were compared based on examples and the SAS macro for power was given as well. RESULTS: The calculation results of SAS programming was consistent with the formula, and SAS programming can directly give the result was more convenient without looking-up table to obtain the relevant parameters.CONCLUSION: It is helpful for investigator to have a better understanding at this programming to calculate sample size and power provided in this paper.

Key words: Measurement data, Non-inferior trial, Sample size, Power, SAS programming