Abstract: AIM: To observe the united effects of photodynamic therapy and soup yanghetang upon soluble interleukin-2 receptor (SIL-2R) of the rats with diabetic foot.METHODS: On the basis of diabetes model by STZ, to establish diabetic foots model through swimming, ice-cubed reducing the heat and liquid nitrogen freezing, which took about 3 weeks divide experimental model of rat into six groups in which 2 groups were respectively treated by He-Ne laser and improved dressing, only He-Ne laser, only improved dressing and Mupirocin, while the model group and normal group had no treatment. Every group was 10 respectively.RESULTS: There were significant difference with changes in the body weight of rats, the amount of drinking water, the score of diabetic foot and the results of blood rheology prompted the group of photodynamic therapy and soup yanghetang with other treatment group. The united effects of photodynamic therapy and soup yanghetang to SIL-2R was distinguished from the normal group, the model and the other the treatment groups (P＜0.01). However, it had no difference from the photodynamic therapy group (P＞0.05).CONCLUSION: The method of the photodynamic therapy diabetic and improved dressing on diabetic foots treatment has the lowest sIL-2R and the most significant ulcer healing. It may provides experimental proof and theoretical basis to further clinic treatment, which has increased a medical treatment and technological method in order to treat diabetic foots.

Key words: Photodynamic, Diabetic foot, Soup yanghetang