Relationship on medication compliance, antipsychotic side-effects and social support in schizophrenia outpatients

Abstract

Abstract: AIM: To explore the relationship on medication compliance, antipsychotic drugs side-effects and social support in schizophrenia outpatients. METHODS: 132 schizophrenia outpatients were were evaluated with Treatment Emergent Symptom Scale(TESS), Social Support Rating Scale (SSRS) and Medication Compliance Scale. The related factors influencing the medication compliance were analyzed. RESULTS: ①The score of Medication Compliance Scale was (9.45±1.29). There were significant differences on Medication Compliance Scale score among different marital state, health insurance and working position. Score of the divorced was lower than unmarried or married patients, patients with health insurance was higher than those without medical insurance, and patients who have a job was higher than have no job. ②Compliance Scale score was significantly negative correlation with TESS (r=-0.727), significantly positive correlation with SSRS (r=0.369). ③Multi-regression showed, TESS Score forecasted compliance negatively. Score of SSRS forecasted compliance positively. CONCLUSION: Antipsychotic drugs side-effect and social support are important factors for medication compliance. Reasonable measures should be taken.

Key words: schizophrenia, antipsychotics, compliance, side-effect, social support

CLC Number:

R749

HANG Rong-hua, LI Ye-ping, WU Ming-fei, LI Rui. Relationship on medication compliance, antipsychotic side-effects and social support in schizophrenia outpatients[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2014, 19(8): 912-915.

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