关键词: 早产低出生体重儿, 神经心理行为, 孤独症, 脑瘫

Abstract: Objective To explore the neuropsychological behavior development states of children with preterm and low birth weight,make early intervene and improve the long-term outcome. Methods All the 14 community health centres of Lianhu district and Beilin district in Xi'an were chosen as the research sites.The resident population of children with preterm and low birth weight was 303,born between October 1st,2011 and September 30th,2013.According to the parents' informed consent,one hundred and forty-four cases (144/303)were included as the the study group and based on random principle,52 term-born children of the same age from the same community were chosen as the control group.The prevalences of cerebral palsy,motor delay and autism spectrum disorders (ASD) were compared between the two groups as well as the level of mental development. Results Among the study group,54 children scored abnormally in GESELL Development Diagnosis Scale (GESELL) scale.There were 10 cases diagnosed ASD,2 cases with cerebral palsy (type spastic),and 11 cases with motor delay.In the control group,3 children showed abnormal results in GESELL scale.Only 1 child was diagnosed motor delay,nobody was with cerebral palsy or ASD.Compared scores of GESELL scale,the scores of the study group were obviously lower than those of the control group,the differences between the two groups were statistically significant(P<0.05). Conclusion s Children with preterm and low birth weight are at high risk of the neural psychological behavior disorders.In the early development,more measures should be taken to supervise the neural and behavior development of these children,since it plays an important role in prevention of the neuropsychological behavior disorders.

Key words: children with preterm and low birth weight, neuropsychological behavior, autism spectrum disorders, cerebral palsy