关键词: 儿童, 过敏性鼻炎, 过敏原, 危险因素

Abstract: Objective To analyze the related factors of allergic rhinitis in 4 to 14-year-old children in Wuhan retrospectively,in order to provide guidance for the prevention and treatment of allergic rhinitis in children. Methods A total of 236 children with allergic rhinitis diagnosed by vitro semi quantitative immunoassay for sensitive screening allergen and receiving treatment in the school hospital of Hubei University and Wuhan General Hospital of the PLA were enrolled in the case group from January 2016 to December 2017. And 60 healthy children in the same period were selected as control group. Single factor analysis and Logistic regression analysis were used to determine risk factors for allergic rhinitis. Results The top five anaphylaxis in children′s allergic rhinitis were as the following order: dermatophagoides (135, 57.2%), house dust mites (92, 38.9%), mold mixture (65,27.5%), dog/cat fur chips (59,25%) and milk (45,19%). Multifactor Logistic analysis showed that family history(OR=2.87, 95%CI: 1.47～3.02), allergy history(OR=2.67, 95%CI:1.72～8.37 ), cesarean section(OR=3.51, 95%CI:1.39～6.70), asthma(OR=2.93, 95%CI:1.52～4.08 ), pet raising(OR=1.67, 95%CI:1.39～4.70 ), disease course for 24 months(OR=1.09, 95%CI: 1.03～1.15), eating seafood(OR=1.78, 95%CI:1.06～4.81 )and second-hand smoke(OR=2.23,95%CI:1.64～3.03 )increased the risk of AR in children,while breastfeeding history was a protective factor for AR (OR=0.68,95%CI:0.53～0.89). Conclusions It is of clinical significance to avoid the allergens for the prevention and treatment of allergic rhinitis in children.

Key words: children, allergic rhinitis, allergens, risk factors