关键词: 儿童, 感染性腹泻, 分离菌株, 抗菌药物, 药敏

Abstract: Objective To investigate the species and antimicrobial resistance of isolated strains from stool of children with infectious diarrhea. Methods The Results of bacterial culture and antimicrobial susceptibility of children with infectious diarrhea were retrospectively analyzed in Xining No.1 People′s Hospital from January 2015 to December 2016. Bacteria identification was performed by Microscan WalkAway-40 system. Antimicrobial susceptibility was performed by Kirby-Bauer method. And Results were judged in accordance with the standard of Clinical and Laboratory Standards Institute (2006 version). Results A total of 112 pathogenic and conditional pathogenic bacteria were detected from 817 stool samples, with positive rate of 13.71%. The major isolated bacteria stains included Shigella(44 stains), enteropathogenic Escherichia coli(29 strains), Salmonella(17 strains), Enterococci(10 strains) and Proteus (6 strains). The major gram-negative bacteria were susceptive to imipenem, the third generation cephalosporins, and beta-lactamase inhibitors. Gram-positive bacteria were susceptive to linezolid and vancomycin. Conclusions The majority of pathogens causing the infectious diarrhea in children is still pathogenic gram-negative bacteria. So it is important to choose antibiotics based on the Results of antimicrobial susceptibility.

Key words: children, infectious diarrhea, isolated strains, antimicrobial agents, drug sensitivity