维生素D缺乏与儿童疾病表观遗传学研究

doi:10.11852/zgetbjzz2018-26-06-13

摘要/Abstract

摘要： 维生素D不仅对骨代谢有着经典的作用,同时在免疫、细胞增殖和分化中有重要的作用。最近的研究发现,孕期维生素D水平也可能通过表观遗传修饰影响到后代儿童期非骨骼系统疾病的易感性,如哮喘,自身免疫性疾病和神经精神疾病等。本文将综述维生素D缺乏与儿童疾病表观遗传学的研究进展。

关键词: 维生素D, 表观遗传学, 儿童疾病

Abstract: Vitamin D plays a classical role in bone health,meanwhile is benefit to immunology,cell growth and differential. Recent evidence indicates that the level of maternal vitamin D may result in non-skeletal system diseases through programming epigenetics,including asthma,autoimmune diseases, neurocognitive disorders and so on. This review will describe the new progress on the association between vitamin D deficiency and programming epigenetics of childhood diseases.

Key words: vitamin D, epigenetics, childhood diseases

中图分类号:

R179

磨晶晶, 仰曙芬. 维生素D缺乏与儿童疾病表观遗传学研究[J]. 中国儿童保健杂志, 2018, 26(6): 626-629.

MO Jing-jing, YANG Shu-fen. Research progress on vitamin D deficiency and programming epigenetics of childhood diseases[J]. journal1, 2018, 26(6): 626-629.

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