关键词: 哮喘, 流行病学, PM2.5, 气温

Abstract: Objective To study the epidemiological characteristics of asthma in outpatients in Hangzhou and its relationship with PM2.5 and temperature, so as to provide basis for clinical prevention and control. Methods The outpatient data of children with asthma in Children′s Hospital Affiliated to Zhejiang University School of Medicine from 2015 to 2019 and the daily weather information from 2015 to 2019 were retrospectively collected, and its correlation was analyzed. Results From 2015 to 2019, a total of 784137 children were diagnosed with asthma in this outpatient department.Children under 3 years old were the main population of asthma, accounting for 49.66%.And children under 7 years old accounted for 84.38%.The prevalence of asthma in autumn and winter was significantly higher than that in other seasons.The number of outpatients was positively related to PM2.5 concentration in children with asthma(r＝0.237,P<0.001), but was negatively correlated with daily maximum temperature(r＝-0.436),daily minimum temperature(r=-0.418),daily temperature difference(r=-0.433),daily mean temperature(r=-0.433)(P<0.001). Conclusions Preschool children have a higher incidence of asthma.Parents are supposed to pay close attention to physical condition of children in autumn and winter with lower temperature and higher PM2.5 so as to prevent the occurrence of severe asthma disease.

Key words: asthma, epidemiology, PM2.5, temperature