关键词: 维生素D, 儿童, 中国

Abstract: Objective To systematically review the prevalence of vitamin D deficiency in healthy Chinese children for nearly 10 years, in order to provide data for public health strategies for children. Methods PubMed, EMbase, CNKI, WanFang Data and VIP database were searched for observational studies over the past 10 years on prevalence of vitamin D deficiency in healthy Chinese children. Stata 14.0 software was used to perform a Meta analysis on the prevalence rate. Results A total of 21 articles were reviewed, with a sample size of 129 283 children aged 0 to 18 years old. Among them, the constituent ratios of sever lacking, deficiency, insufficient, adequate, excess, intoxication were 2.46%(1.03%—4.47%), 21.57%(13.65%—30.72%), 28.71%(20.83%—37.35%), 55.80%(42.19%—68.97%), 0.30%(0.17%—0.46%) and 0.11%(0.07%—0.17%), respectively. The deficiency rate gradually increased with the increasing of age, with the lowest rate of 11.06% in the infant group and the highest rate of 56.14% in the adolescent group, the difference was statistically significant(P=0.003). The deficiency rate of children were higher in North China than in South China(P=0.249). The rate of Vitamin D deficiency in Spring and Winter were higher than that in Summer and Fall(P=0.168),but the difference was not significant(P＞0.05). Conclusion Vitamin D level in Chinese healthy children are not optimistic, and active efforts should be made to improve the overall vitamin D level of Chinese children.

Key words: vitamin D, children, China